dbco-peg-4-pfp ester

4-benzyloxycarbonylamino-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester is a biologically active compound used as an intermediate in the synthesis of a variety of compounds.

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

4-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester is a substituted piperidine derivative widely used in organic synthesis as a linker to form peptide and peptidomimetic molecules, and is widely used in peptide synthesis and peptide mimicry, as well as in the synthesis of pharmaceuticals, biopolymers and other organic molecules.

Mal-PFP ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG13-NHS ester is a pegylated PROteolysis-TArgeting Chimera (PROTAC) linker, serving as a valuable tool for PROTAC synthesis[1].

N3-PEG4-C2-Pfp ester is a four-unit polyethylene glycol linker, noncleavable in nature, specifically employed in the fabrication of antibody-drug conjugates (ADCs).

(±)4(5)-EpDPA methyl ester is a derivative of (±)4(5)-EpDPA which is stable enough to ship and handle routinely. The active free acid can be regenerated from the methyl ester by careful base hydrolysis. (±)4(5)EpDPA is a CYP450 metabolite of DHA which can be further metabolized to the diol metabolite. There are no published reports on the biological activity of (±)4(5)-EpDPA methyl ester at this time.

DBCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-Sulfo-NHS ester sodium is a cleavable linker predominantly employed in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-PEG1-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction[2].

DBCO-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG4-PFP ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs).

Hydroxy-PEG2-C2-PFP ester, a PEG/Alkyl/ether-based PROteolysis TArgeting Chimeric (PROTAC) linker, is suitable for the synthesis of PROTACs.

N-DBCO-N-bis(PEG2-C2-NHS ester) is a Polyethylene Glycol (PEG) derived linker that finds utility in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

DBCO-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

L-Aspartic Acid 4-Benzyl Ester is a chelating agent that forms stable complexes with metal ions. It has been used to study the effect of metal ions on enzyme activity and to investigate the role of metal ions in the regulation of gene expression.

Mal-PEG4-PFP ester is a non-cleavable antibody-drug conjugate (ADC) linker that incorporates a Maleimide moiety, a 4-unit Polyethylene Glycol (PEG) backbone, and a Pentafluorophenyl (PFP) ester.

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor acting as a toxin payload in antibody-drug conjugates, is conjugated to a DBCO-(PEG)3-vc-PAB linker.

Azido-PEG8-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG1-PFP ester, an alkyl/ether-based PROTAC linker, is utilized in PROTAC synthesis.

DBCO-PEG4-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NHPI-PEG2-C2-Pfp ester is a noncleavable 2-unit polyethylene glycol (PEG) linker widely employed in the synthesis of antibody-drug conjugates (ADCs).

DBCO-NHS ester is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).

Mal-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1].

Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative.

Diketone-PEG11-PFP ester serves as a PEG-based PROTAC linker for PROTAC synthesis[1].

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized for synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Hydroxy-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Cyclooctyne-O-PFP ester is a used as an ADC cytotoxin, which connects antibody and linker[1].

DBCO-CONH-S-S-NHS ester is a disulfide-linked ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-NHCO-PEG5-NHS ester is a polyethylene glycol (PEG)-based linker utilized in the synthesis of PROTACs[1].

Ald-Ph-amido-PEG2-C2-Pfp ester is a non-cleavable 2-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.

Malic acid 4-Me ester is a natural product for research related to life sciences. The catalog number is TN4487 and the CAS number is 66178-02-7.

Mal-amido-PEG3-C1-PFP ester, a non-cleavable 3 unit PEG ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs).'

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].

Ald-Ph-amido-PEG1-C2-Pfp ester is a non-cleavable 1-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.

DBCO-PEG2-NHS ester is a click chemistry reagent featuring an azide group and an NHS ester, designed for copper-free Click Chemistry. It specifically and efficiently reacts with primary amines (e.g., lysine residue side chains or aminosilane-coated surfaces) under neutral or slightly basic conditions to form stable covalent bonds. The inclusion of a hydrophilic PEG spacer enhances water solubility and provides a flexible linkage, reducing steric hindrance during ligation. This compound, intended for research use only [1], is ideal for applications requiring precise and efficient bioconjugation.

Bis-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NHPI-PEG3-C2-Pfp ester is a trifunctional polyethylene glycol (PEG) linker molecule, employed specifically in the fabrication of antibody-drug conjugates (ADCs).

Mal-PEG2-PFP ester, an alkyl/ether-based PROTAC linker, facilitates the synthesis of PROTACs.

DBCO-NHCO-S-S-NHS ester is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-NHCO-C4-NHS ester is an alkyl chain-derived PROTAC linker applicable for PROTACs synthesis[1].

Bis-PEG5-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

BCN-PEG3-VC-PFP ester is a three-unit PEG ADC linker that can be cleaved, and it is commonly employed in the synthesis of antibody-drug conjugates (ADCs) [1].