dexamethasone 21-phosphate disodium

Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone.

N-Acetyl-α-D-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, plays a crucial role as an intermediate in the biosynthesis of N-linked glycoproteins. Additionally, it serves as a metabolic precursor for the synthesis of bacterial cell-wall components, particularly teichoic acid and murein [1].

Etoposide phosphate disodium (BMY-40481 disodium), a phosphate ester prodrug of etoposide, functions as a potent chemotherapeutic agent by selectively inhibiting topoisomerase II, hindering the re-ligation of DNA strands. It is regarded as the active equivalent of etoposide, effectively inducing cell cycle arrest, apoptosis, and autophagy in cancer cells.

Betamethasone 21-phosphate is a synthetic glucocorticoid.1It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model of parainfluenza-3 viral infection when administered at a dose of 8 mg/kg but does not prevent airway hyperresponsiveness after infection.2Betamethasone 21-phosphate inhibits cell infiltration into the aqueous humor in a rat model of endotoxin-induced uveitis when administered topically or subcutaneously at doses of 0.01-1% or 1 mg/kg, respectively.3It increases maximal lung pressure volume curves in fetal sheep when administered to pregnant ewes at 0.75 gestation at doses of 80 and 170 μg/kg.1Betamethasone 21-phosphate increases body weight, impairs learning and memory, increases anxiolytic behavior, and reduces hippocampal neurogenesis in CD-1 mice but reduces body weight and increases neurogenesis with no effect on anxiety in high-anxiety DBA/2 mice when administered at a dose of approximately 25 mg/kg per day in the drinking water for seven weeks.4Formulations containing betamethasone 12-phosphate and betamethasone acetate have been used in the treatment of severe allergic conditions and a variety of immune-related conditions. 1.Loehle, M., Schwab, M., Kadner, S., et al.Dose-response effects of betamethasone on maturation of the fetal sheep lungAm. J. Obstet. Gynecol.202(2)186.e181-186.e187(2010) 2.Leusink-Muis, A., Ten Broeke, R., Folkerts, G., et al.Betamethasone prevents virus-induced airway inflammation but not airway hyperresponsiveness in guinea pigsClin. Exp. Allergy29(Suppl. 2)82-85(1999) 3.Tsuji, F., Sawa, K., Kato, M., et al.The effects of betamethasone derivatives on endotoxin-induced uveitis in ratExp. Eye Res.64(1)31-36(1997) 4.Aiello, R., Crupi, R., Leo, A., et al.Long-term betamethasone 21-phosphate disodium treatment has distinct effects in CD1 and DBA/2 mice on animal behavior accompanied by opposite effects on neurogenesisBehav. Brain Res.278155-166(2015)

D-Fructose 1-phosphate disodium salt, a derivative of fructose, serves as a crucial intermediate in glucose metabolism.

Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.

Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.

Dexamethasone Sodium Phosphate (Dexadreson) , an interleukin receptor modulator, has anti-inflammatory and immunosuppressant effects. It belongs to a potent glucocorticoid class of steroid synthetic drugs.

2-Deoxyribose 5-phosphate disodium acts as a substrate for the enzyme 2-deoxyribose-5-phosphate aldolase (DERA), which is categorized under class I aldolases. DERA efficiently facilitates the reversible aldol condensation reaction independently, without the need for any cofactors [1].

2-Deoxy-D-glucose 6-phosphate disodium, a derivative of glucose analog 2-Deoxy-D-glucose, is synthesized in mammalian cells through hexokinase activity on 2-DG. It functions as a competitive inhibitor of glucose metabolism, specifically obstructing glycolysis by targeting hexokinase.

α-Tocopherol phosphate (alpha-Tocopherol phosphate) is an antioxidant that scavenges UVA1-induced reactive oxygen species (ROS) and protects against long-wave UVA1-induced cell death. alpha-Tocopherol phosphate disodium impedes endothelial progenitor cell apoptosis, enhances endothelial progenitor cell migration under high glucose/low oxygen conditions and promotes angiogenesis. α-Tocopherol phosphate disodium (Vitamin E phosphate disodium) prevents apoptosis, enhances migration of endothelial progenitor cells under high glucose/low oxygen conditions and promotes angiogenesis.

Creatinine Phosphate Disodium Salt is a useful organic compound for research related to life sciences and the catalog number is T125448.

D-Fructose-6-phosphate disodium salt (D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT) is an important intermediate in the Carbohydrates pathway. The interconversion of glucose-6-phosphate and fructose-6-phosphate, the second step of the Embden-Meyerhof glycolytic pathway.

Tedizolid phosphate is a novel antibacterial prodrug. Tedizolid phosphate is a next-generation oxazolidinone with activity against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus spp. It also has effective activity a

D-Glucose 6-phosphate disodium salt is a compound widely present in biological systems. It is a molecule formed when glucose undergoes phosphorylation at the 6th carbon. This compound participates in various metabolic regulatory pathways within the body, including the pentose phosphate pathway and glycolysis.

α-D-Glucose 1-phosphate disodium salt is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.

Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a corticosteroid with anti-inflammatory activity that promotes the polarization of M1 to M2 macrophages by decreasing the secretion of pro-inflammatory cytokines, and is used in the study of keloids and rheumatoid arthritis.

α-D-Glucose-1-phosphate disodium hydrate serves multiple roles in medical and biochemical applications, including as a precursor in the synthesis of glucuronic acid, a cytostatic compound crucial for cardiopathic therapy, an antibiotic, an immunosuppressive agent, and a component in circulatory system therapy [1].

Naphthol AS-GR phosphate disodium, a substrate for both acid and alkaline phosphatases, exhibits intense green fluorescence, making it valuable for histochemical studies [1].

Disodium Phosphate (Sodium hydrogen phosphate) is commonly used as a food additive and also acts as a corrosion inhibitor.

D-Ribose 5-phosphate disodium dihydrate participates in the pentose phosphate pathway and is an intermediate in the pentose phosphate pathway, and is used in studies of ocular diseases and endocrine and metabolic disorders caused by riboflavin deficiency.