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duocarmycin sa

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Duocarmycin SA
T11118130288-24-3
Duocarmycin SA is an extremely potent cytotoxic agent and antitumor antibiotic that induces sequence-selective alkylation of duplex DNA, with an IC50 of 10 pM. It demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells when combined with proton radiation in vitro.
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(S)-Seco-Duocarmycin SA
T12813152785-82-5
(S)-Seco-Duocarmycin SA, a DNA alkylator, serves as an ADC cytotoxin for antibody-drug conjugates.
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10-14 weeks
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Seco-Duocarmycin SA
T12813L144667-38-9
Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.
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10-14 weeks
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Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA
T182932259318-49-3
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is an antibody-drug conjugate linker, integrating the antitumor antibiotic Duocarmycin SA via the Mal-PEG4-VC-PAB-DMEA-Seco linker, aimed at targeted cancer therapy.
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