estriol 3-β-d-glucuronide

Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membranes with Kd values of 85 and 164 μM, respectively. It competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide and is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc).

6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) is a chromogenic substrate for β-glucuronidase and can be utilized in the histochemical analysis of β-glucuronidase activity.

Oroxylin A 7-O-β-d-glucuronide was a new alkaloid which found in the bulbs of Lycoris radiata.

Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside is a natural peoduct isolated from Arabian jasmine

(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol is a useful research compound for many research applications, including the fields of chemistry and life sciences, among others.

3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one is a compound that has been extensively investigated for the treatment of a variety of disorders including tumors, Alzheimer's and Parkinson's diseases, anti-inflammatory drugs, and analgesic agents.

2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).

1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea is a useful organic compound for research related to life sciences. The catalog number is T67700 and the CAS number is 1144075-47-7.

Pyrazinecarboxamide, 3,4-dihydro-4-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-oxo- is a useful organic compound for research related to life sciences. The catalog number is TNU0422L and the CAS number is 356783-01-2.This compound is unstable in powder form and other related salt forms are recommended.

1. Gypsogenin-3-O-glucuronide (Methyl gypsogenin 3-O-beta-D-glucuronopy) shows inhibitory activity toward pancreatic lipase with IC5 value of .29 mM, and the free carboxylic acid groups in position 28 within its chemical structures are required for enhancement of pancreatic lipase inhibition.

Glycyrrhetic acid 3-O-β-D-glucuronide is a potent sweetener (relative sweetness to sucrose: x 941).

Peimisine 3-O-β-D-glucopyranoside (Compound 1), a steroid alkaloid isolated and purified from Fritillaria unibracteata, demonstrates a moderate protective effect against rotenone-induced neurotoxicity in the PC12 cell line [1].

Hederagenin 28-O-{β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester}3-O-{α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl} is a saponin known for its antitumor and anti-inflammatory properties [1].

3-O-Methylquercetin 4',7-di-β-D-glucopyranoside, a flavonoside, is isolated from *Ophioglossum pedunculosum* [1].

Fmoc-Thr(GalNAc(Ac)3-β-D)-OH impedes cancer cell proliferation by selectively interacting with complex oncogenic pathways and enhancing the immune response [1].

Deferiprone O-β-D-glucuronide, a new orally active iron chelator, effectively reduces the iron burden in patients with β-thalassemia [1].

D-3 (phosphorpeptide) is an efficient, simple, and specific agent for eliminating iPSCs.

1-(3',5'-dimethoxy)phenyl-2-[4''-O-β-D-glucopyranosyl (6→1)-O-α-L-rhamnopyranosyl]phenylethane showed cytotoxic activities to Hela and hep2 cell lines.

Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), functions as a weak agonist at the antidiuretic receptor and a potent agonist at the pituitary corticotrope receptor [1].

H-D-Phe(3-F)-OH, with catalog number T67306 and CAS number 110117-84-5, is a valuable organic compound for research in life sciences.

Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside exhibits antioxidant activity.

(S)-Ibuprofen acyl-β-D-glucuronide ((S)-Ibuprofen glucuronide) serves as a crucial analytical tool in examining the metabolic pathways and pharmacokinetic profile of S-ibuprofen, a widely used non-steroidal anti-inflammatory drug. This compound is specifically an acylglucuronic acid metabolite of S-ibuprofen, synthesized primarily in the liver [1].

3-O-Benzyl-1,2:5,6-di-O-isopropylidene-alpha-D-allofuranose is a Carbohydrate.

Nucleoside Derivatives - 8-Aza-7-deaza purine nucleosides, Halo-nucleosides

5-O-TBDPS-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside is a carbohydrate.

c-Kit-IN-3 D-tartrate is a potent and selective c-KIT kinase inhibitor (IC50s: 4 nM, 8 nM for c-KIT wt, and c-KIT T670I).

H-3-D-Pal-OH.HCl, an amino acid derivative, has diverse applications in life science research.

3-Deoxy-3-fluoro-1,2:5,6-di-O-isopropylidene-a-D-gluco-pentofuranose is a Carbohydrate Derivative.

Quercetin 3-O-(6-O-malonyl)-b-D-glucoside is a useful organic compound for research related to life sciences. The catalog number is T123838 and the CAS number is 96862-01-0.

Nucleoside Derivatives - 7-Deaza-8-aza purine nucleosides; Halo-nucleosides; 6-Modified purine nucleosides

Nucleoside Derivatives - C-Nucleosides, Pyridine nucleosides

2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuranosyl)-9H-purine is a nucleoside derivative, specifically a 3'-deoxy nucleoside and halo-nucleoside, serving as a scaffold and template.

D-Glyceraldehyde 3-phosphate (Triose phosphate), a pivotal molecule in cellular metabolism, serves as a crucial intermediate in glycolysis, gluconeogenesis, and the Calvin cycle, and plays a significant role in the biosynthesis of tryptophan and thiamin [1].

Tolmetin β-D-Glucuronide has reactive properties with human serum albumin, allowing identification of the binding site and reaction mechanism by tandem mass spectrometry.

Quinovic acid 3-O-(3',4'-O-isopropylidene)-beta-D-fucopyranoside is a natural product for research related to life sciences. The catalog number is TN4885 and the CAS number is 182132-59-8.

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside) is a compound extracted from the leaves of Ginkgo biloba with notable antioxidant properties.

1-b-D-(3-Methoxy naphthalen-2-yl)-2’-deoxyriboside; 1,4-Anhydro-2-deoxy-1-C-(3-methoxy)-naphthalenyl)-D-erythro-pentitol is a useful organic compound for research related to life sciences. The catalog number is TNU1641 and the CAS number is 1117893-19-2.

2-Amino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is a fluoro-modified nucleoside, halo-nucleoside, and arabino-nucleoside.

Nucleoside Derivatives –Fluoro-modified nucleosides, 6-Modified purine nucleosides, 3’-Modified nucleosides

Nucleoside Derivatives - Fluoro-modified nucleosides; 6-Modified purine nucleosides, 3’-Modified nucleosides

2,6-Dichloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is a Fluoro-modified nucleoside; Halo-nucleoside; Arabino-nucleoside.

Propofol β-D-glucuronide is a metabolite of propofol sulfate, a short-acting anesthetic agent. The metabolite is generated through the glucuronidation of propofol by uridine diphosphate glucuronosyltransferases, and propofol metabolism appears to occur more rapidly in women than in men. [1] [2]

Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) is a natural product with significant pharmacological effects on the cardiovascular system.

(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol , which is a metabolite of propranolol. The apparent half-life of (±)-4-hydroxy propranolol β-D-glucuronide is similar to propranolol and 4-hydroxy propranolol. Propranolol is a β-adrenergic antagonist, and the active enantiomer, (S)-(-)-propranolol , has log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively.

1-[(5E)-3-O-[(Bis-di-isopropyl amino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil is a Nucleoside Phosphoramidite; Nucleoside Derivative - Phosphorus-containing nucleotide; 5'-Modified nucleoside.

5-O-benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose is a Carbohydrate; Used for modified nucleoside.

Nucleoside Derivatives –Fluoro-modified nucleosides, 5-Modified pyrimidine nucleosides, Arabino-nucleosides, 2’-Modified nucleosides

9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a Nucleoside Derivative used as a 3'-Deoxy nucleoside, Halo-nucleoside, scaffold, and template.