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By Tag By Expression System- HEK293 Cells(1)
By Species- Human(1)
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Results for "
flj-90062
" in TargetMol Product Catalog- Recombinant Protein1
CompareDCAD2,LRP-6,FLJ90421,LRP6,FLJ90062
TMPK-00744
Dickkopf-related protein 1 (DKK-1), a ligand for the WNT coreceptors low-density lipoprotein receptor-related proteins 5 and 6 (LRP-5 and LRP-6) and an inhibitor of WNT β-catenin signaling, effectively inhibits pericyte activation, detachment, and transition to myofibroblasts in vivo in response to kidney injury, resulting in attenuated fibrogenesis, capillary rarefaction, and inflammation.LRP-6 interacts closely with PDGF receptor β and TGF-β receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT β-catenin.
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