fmoc-nh-ethyl-ss-propionic acid

Fmoc-NH-ethyl-SS-propionic acid is a cleavable linker compound used in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.

Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands to form PROTAC molecules, thereby enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker employed in PROTAC synthesis [1].

Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Fmoc-NH-PEG10-acid, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Boc-NH-C4-acid is a PROTAC linker of the Alkyl ether class, utilized in the synthesis of PROTAC1 for the degradation of EED, EZH2, and SUZ12 in [PRC2].

Fmoc-azetidine-3-carboxylic acid is a valuable compound for life sciences research (catalog number: T65634, CAS number: 193693-64-0).

Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 4 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a polyethylene glycol (PEG)-based linker used in the development of proteolysis targeting chimeras (PROTACs)[1].

Boc-aminooxy-ethyl-SS-propanol is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Cbz-NH-PEG24-C2-acid is a PEG-based linker for PROTACs that enables selective protein degradation by linking two essential ligands, crucial for forming PROTAC molecules, and leveraging the ubiquitin-proteasome system within cells.

Acid-PEG3-SS-PEG3-acid is a cleavable six-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Fmoc-N-bis-PEG3-NH-Boc is a cleavable ADC linker compound with three PEG units, used in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-aminooxy-PEG12-acid, a PEG-based PROTAC linker, is employed for synthesizing PROTACs[1].

m-PEG4-phosphonic acid ethyl ester is a PEGylation-based linker used in the design and synthesis of PROTACs, which are heterobifunctional molecules that facilitate targeted protein degradation[1].

Azidoethyl-SS-propionic acid is an ADC linker, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. It possesses cleavable properties, allowing for the controlled release of drug payloads.

Fmoc-NH-pentanoic acid-NHS-SO3Na is a PROTAC linker molecule derived from an alkyl chain, facilitating the synthesis of PROTACs[1].

m-PEG5-phosphonic acid ethyl ester, a polyethylene glycol (PEG)-derived linker, is commonly used in constructing proteolysis targeting chimeras (PROTACs) [1].

Fmoc-NH-PEG16-CH2CH2COOH is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

FN-1501-propionic acid, a CDK2/9 ligand, in conjunction with a CRBN ligand, has been utilized in the design of a PROTAC CDK2/9 degrader.

Fmoc-NH-PEG6-CH2CH2COOH is a cleavable linker frequently used in the synthesis of antibody-drug conjugates (ADCs)[1].

Boc-NH-ethyl-SS-propionic acid, an ADC linker compound, is utilized for the synthesis of antibody-drug conjugates (ADCs)[1].

Thiol-PEG3-phosphonic acid ethyl ester, a PEG-based linker, serves as a valuable component in the synthesis of PROTACs[1].

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Fmoc-NH-PEG1-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for forming PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system in cells.

Fmoc-N-amido-PEG20-acid is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs[1].

Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) for the preparation of neolymphostin-based ADC precursors, specifically for site-specific cysteine mutant trastuzumab-A114C conjugation[1].

Cbz-NH-PEG2-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two key ligands essential for PROTAC molecule formation, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Acid-PEG2-ethyl propionate is a valuable organic compound for life sciences research (catalog number: T66862, CAS number: 886362-90-9).

Fmoc-N-amido-PEG7-acid, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Cbz-NH-PEG36-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands vital for PROTAC molecule formation. It enables selective protein degradation by utilizing the cell's ubiquitin-proteasome system.

NH-bis(PEG3-acid) is a PEG-based linker utilized in PROTACs, connecting two essential ligands crucial for creating PROTAC molecules. This linker leverages the ubiquitin-proteasome system within cells to enable selective protein degradation.

Fmoc-NH-PEG11-CH2COOH is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation through the ubiquitin-proteasome system within cells.

Amino-ethyl-SS-PEG3-NHBoc is a cleavable 3-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Cbz-NH-PEG5-C2-acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

DNP-NH-PEG2-C2-acid is a PEG-based linker for PROTACs, which connects two essential ligands critical for PROTAC molecule formation, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Fmoc-NH-PEG12-CH2COOH is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Boc-PEG4-phosphonic acid ethyl ester is a polyethylene glycol (PEG) derived linker compound used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs) [1].

m-PEG6-C6-phosphonic acid ethyl ester is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

Cbz-NH-PEG3-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands crucial for PROTAC molecule formation. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker utilized in synthesizing antibody-drug conjugates (ADCs)[1].

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Aminoethyl-SS-propionic acid is an ADC linker compound employed in ADC synthesis [1]. It functions as a cleavable linker in the conjugation of antibodies with drugs, allowing for targeted drug delivery.

Fmoc-11-aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Fmoc-11-aminoundecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Carboxy-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker used in the synthesis of PROTACs, serving as an integral compound [1].

Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable linker for antibody-drug conjugates (ADCs)[1], used in the synthesis of ADCs to facilitate the covalent attachment of drugs to antibodies through stable amide bond formation.

Acid-PEG2-SS-PEG2-acid, a 4-unit PEG ADC linker with cleavable bonds, is used in the synthesis of antibody-drug conjugates (ADCs)[1].