Deacetyl ganoderic acid F (DeGA F), a triterpenoid extracted from Ganoderma lucidum, inhibits lipopolysaccharide (LPS)-induced inflammation in vitro and in vivo.

Ganoderic acid SZ is a natural product. The catalog number is TN4104 and the CAS number is 865543-37-9. Ganoderic acid SZ can be used as a reference standard.

Ganoderic acid T, a natural compound isolated from Ganoderma lucidum [1], exhibits various pharmacological properties.

Ganoderic acid Me, a triterpenoid present in Ganoderma lucidum [1], exhibits various biological activities.

Ganoderic acid Mk (GA-Mk), a triterpenoid acid derived from Ganoderma lucidum mycelia, exhibits potent anti-proliferative properties and can induce apoptosis in HeLa cells through a mitochondria-mediated pathway, making it significant for cervical cancer research [1] [2].

Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic acid C1 has anti-tumor-promoting activity. It is moderately active inhibitors against HIV-1 prot

A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), the composition is suitable for the treatment or prophylaxis of colon ca

Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating.

23S-hydroxy-11,15-dioxo-ganoderic acid DM is a natural product

Ganoderic acid D2 is a natural product

Methyl Ganoderic acid B, a triterpenoid isolated from Ganoderma lucidum, exhibits neuronal survival-promoting effects similar to nerve growth factor (NGF-like) [1].

Ganoderic acid L is a natural product from the fruiting body of the fungus Ganoderma lucidum (Reishi).

Ganoderic acid J, a natural terpenoid extracted from Ganoderma lucidum fungus, exhibits anti-inflammatory properties.

Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane pr

Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.

Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has antinociceptive effect

1. Ganoderic acid C6 has antinociceptive activity.

Ganoderic acid GS-1, an extensively oxygenated lanostane-type triterpenoid, exhibits anti-HIV-1 protease activities, displaying an IC50 value of 58 μM [1].

The binding affinities of ganoderic acid DM and ganoderic acid Z (ΔGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal mol-1);Ganoderic acid DM is a potential source of anti-influenza ingredient, with novel binding pattern and advantage over oseltamivir, it has steric hindrance on the 150 cavity of N1 protein, and exerts activities across the H274Y and N294S mutations, is the attractive candidates of novel neuraminidase (NA) inhibitors.Ganoderic acid zeta has cytotoxicity in vitro against Meth-A and LLC cell lines.

Ganoderic acid AM1 treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with IC(50) values of 19.8+/-0.7 microM.

Ganoderic acid I is a natural product from Ganoderma lucidum .

Ganoderic acid G is isolated from the surface of Ganoderma lucidum tube layer.

Ganoderic acid ε, a naturally occurring terpenoid, is extracted from the Fungus Ganoderma lucidum. This compound possesses an ED 50 value of 12.2 μg/mL, as demonstrated in its impact on Meth-A tumor cells.

Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-kappaB, resulting in the down-regulation of expression of Cdk4.

Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum

1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human

Ganoderic acid T-Q and TR are two inhibitors of H5N1 and H1N1 NAs.

Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities.

23-Dihydroganoderic Acid N has anticancer effects.

Ganoderic acid GS-2 inhibits the activity of the human immunodeficiency virus-1 (HIV-1) protease.

Ganoderic acid T1, a deacetylated derivative of Ganoderic acid T, diminishes mitochondrial membrane potential and triggers cell apoptosis by activating caspase-9 and caspase-3, thus impairing the antioxidant defense system of cancer cells. Additionally, it elevates intracellular ROS levels, yielding pro-oxidant activities and cytotoxicity [1].

Ganoderic acid Df, a lanostane-type triterpenoid isolated from the fruiting body of Ganoderma lucidum, potently inhibits aldose reductase with an IC 50 of 22.8 ± 0.6 μM [1].

Ganoderic acid LM2 exhibits potent enhancement of ConA-induced mice splenocytes proliferation in vitro.

1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 microM.

Ganoderic acid TR, a triterpene compound isolated and exported from the medicinal Ganoderma lucidum, is an inhibitor of H5N1 and H1N1 NAs with broad-spectrum antiviral activity.

Ganoderic acid TN is a natural product. The catalog number is TN4106 and the CAS number is 112430-64-5. Ganoderic acid TN can be used as a reference standard.

Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities.

Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.

Ganoderic acid R, exhibiting notable anticancer properties, effectively hampers tumor growth through apoptosis induction in both multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and sensitive tumor cell line (KB-A-1), demonstrating significant cytotoxicity.

Ganoderic acid Mf, an antitumor triterpenoid, selectively induces apoptosis in cancer cells through a mitochondria-mediated pathway while demonstrating high selectivity between normal and cancer cells. It also arrests the cell cycle in the G1 phase [1].

Ganodermic acid S, as a membrane acting agent isolated from the fungus Ganoderma lucidum, exerts multiple effects on human platelet function.

12-Hydroxyganoderic acid D is a natural product

12β-Acetoxyganoderic Acid θ, a triterpenoid extracted from G. lucidum [1], exhibits potential biological activities.

20-Hydroxyganoderic acid G is a lanosterane triterpenoid obtained from the ethanolic extract of Ganoderma curtisii (Ganoderma curtisii) cotyledons. 20-Hydroxyganoderic Acid G inhibited LPS-activated BV-2 microglia, with an IC50 value of 21.33 μM. 20-Hydroxyganoderic Acid G was used to study neuroinflammatory diseases associated with LPS activation. 20-Hydroxyganoderic Acid G was used to study neuroinflammatory diseases associated with microglia activated by LPS.

Ganoderic acid 24, chemically designated as lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid, exhibits significant cytotoxicity against various cancer cell lines, including human lung cancer cells CH27, melanoma cells M21, and oral cancer cells HSC-3 [1].

The oxygenated sterols( 26-oxygenosterols ganoderol A, ganoderol B, ganoderal A, and ganoderic acid Y) from G. lucidum can inhibit cholesterol biosynthesis via conversion of acetate or mevalonate as a precursor of cholesterol.

Ganorbiformin B, a lanostane triterpenoid, belongs to the same structural class as ganoderic acids, sharing the lanostane skeleton. It is the C-3 epimer of ganoderic acid T, known for its potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra [1].