gossypol-acetic acid

Gossypol acetic acid (AT101), a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID.

(R)-(-)-Gossypol acetic acid (AT101 acetate), the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 μM, 0.48 μM, and 0.18 μM, respectively; it does not inhibit the BIR3 domain or BID. [Phase 2]

(S)-Gossypol acetic acid is the isomer of a natural product Gossypol.

5-Hydroxyindole-3-acetic acid (5-HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels of these substances may be measured in the urine to test for carcinoid tumors (NCI).

2-(4-Methoxyphenyl)acetic acid, a plasma metabolite, is highly sensitive and specific and can be used as a bioindicator to differentiate non-small cell carcinoma patients from healthy controls.

5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.

2-(3,5-dibromo-4-methoxyphenyl)acetic acid (3,5-Dibromo-4-methoxyphenyl acetic acid) is a marine derived natural products found in Ianthella quadrangulata.

6-Bromo-1H-indole-3-acetic acid methyl ester (Methyl 6-Bromoindole-3-acetate) is a marine derived natural products found in Pseudosuberites hyalinus.

7-Amino-4-methylcoumarin-3-acetic acid [7-Amino-4-methylcoumarin] is a more suitable substrate for enteropeptidase compared to GD(4)K-NA.

2-(2-Methylbenzamido)acetic acid (O-Toluric acid) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Methylhippuric acid is a metabolite of xylene which is an aromatic hydrocarbon widely used as a solvent.

Compound 29, 2-(3-Hydroxy-2-oxoindolin-3-yl)acetic acid, is a natural polyphenol found in hop bract [1].

2-Aminothiazol-4-acetic acid acts by inhibiting the activity of certain enzymes and proteins related to inflammation, tumor growth and oxidative stress, and has anti-inflammatory, anti-tumor and anti-fungal activities.

Imidazol-1-yl-acetic acid is a natural product used in life sciences research (Catalog No. T67657, CAS No. 22884-10-2).

2-(1-methyl-1H-imidazol-4-yl)acetic acid (2-(1-methylimidazol-4-yl)acetic acid) is a plasma histamine derivative that is a biomarker for identifying lymphangioleiomyomatosis.

Phenyl-ac-Gly-OH is an endogenous metabolite that activates β2AR and can be used in the study of ischemia reperfusion-induced cardiac injury.