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haec

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  • Inhibitors & Agonists
    3
    TargetMol | Activity
Tirofiban hydrochloride monohydrate
Tirofiban Hydrochloride,MK-383 Hydrochloride
T2537150915-40-5
Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb IIIa antagonist.
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TargetMol | Inhibitor Hot
Tirofiban
L700462,Aggrastat,MK383
T6182144494-65-5
Tirofiban (L700462) (MK-383) is a selective palate GPIIb IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
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4-6 weeks
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CAY10789
T60439123226-28-8
CAY10789 (compound 6) is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist with an IC50 of 2.80 μM and a GPBAR1 (G-protein-coupled bile acid receptor 1) agonist with an EC50 of 3 μM. It significantly decreases U937 cell adhesion to HAEC and reduces TNF-α expression. CAY10789 demonstrates promising metabolic stability and excellent pharmacokinetics, making it suitable for studying colitis, metabolic syndromes, and other GPBAR1 CysLT1R-related diseases [1].
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6-8 weeks
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