hipsc

CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1 expression.CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress.

Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).

HIF-PHD-IN-3 is a potent hiPSC-CM cardioprotective scaffold with potential inhibitory effects on HIF-PHD, regulates heme oxygenase-1, and can be used to study anaemia.

Oct4 Inducer-2, an OCT4 inducer, sustains hiPSC formation by enhancing endogenous OCT4 expression and has applications in anti-aging research [1].