hydroxypeg12ch2boc

Methyl 2-(Boc-aMino)-2-(oxetan-3-yl)acetate can be used as a building block for the synthesis of various biologically active molecules such as peptides, proteins, and nucleic acids.

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Hydroxy-PEG12-CH2-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This compound facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-2-Pal-OH is an amino acid derivative and has a wide range of applications in life science related research.

(2-Pyridyldithio)-PEG2-Boc is a polyethylene glycol-based PROTAC linker used in the synthesis of PROTACs [1].

Boc-Arg(Z)2-OH is an amino acid derivative and has a wide range of applications in life science related research.

SARS-CoV-2-IN-12, a potent inhibitor of the SARS-CoV-2-related 3C-like protease (K_i=32.1 pM), plays a crucial role in preventing SARS-CoV-2 viral replication, showcasing potential significance in COVID-19 research.

VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent inhibitor of VEGFR-2 with an IC50 of 0.037 μM and demonstrates anti-tumor effects.

Boc-(R)-2-thienylglycine, with catalog number T65017 and CAS number 74562-03-1, is a valuable organic compound for research in the life sciences.

Boc-Phe(2-Me)-OH is an amino acid derivative and has a wide range of applications in life science related research.

11R,12-Dihydroxyspirovetiv-1(10)-en-2-one is a natural product for research related to life sciences. The catalog number is TN2593 and the CAS number is 62574-30-5.

Boc-D-2-Pal-OH is an amino acid derivative with a wide range of applications in life sciences research.

Boc-D-2-Nal-OH is a useful organic compound for research related to life sciences. The catalog number is T66189 and the CAS number is 76985-10-9.

Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

COX-2-IN-12 (compound 3b) is a potent and selective COX-2 inhibitor with an IC50 of 19.98 μM, demonstrating anti-inflammatory properties and safety in in-vivo acute toxicity studies [1].

2-(2-Acetoxy-12-hydroxytridecyl)-4,6-dihydroxybenz is a useful organic compound for research related to life sciences. The catalog number is T126038 and the CAS number is 133361-20-3.

Bcl-2-IN-12 (Compound 1) is a potent Bcl-2 inhibitor with an IC50 value of 6 nM, used in cancer research [1].

Boc-2-Nal-OH is a useful organic compound for research related to life sciences. The catalog number is T66060 and the CAS number is 58438-04-3.

Boc-Lys(2-Cl-Z)-OH (Catalog number: T67521, CAS number: 54613-99-9) is an important organic compound utilized in life sciences research.

SARS-CoV-2 Mpro-IN-12 (compound D026) is an inhibitor of the main protease (Mpro) of SARS-CoV-2, demonstrating antiviral properties [1].

(Rac)-Phorbol-12-(2-methylbutyrate), a natural product, can be isolated from croton oil [1].

Boc-D-Tyr(2-Br-Z)-OH, with catalog number T66218 and CAS number 81189-61-9, is a valuable organic compound for life sciences research.

Boc-Tyr(2-Br-Z)-OH is a useful organic compound for research related to life sciences. The catalog number is T67623 and the CAS number is 47689-67-8.

Boc-D-Phe(2-Me)-OH, an amino acid derivative, has diverse applications in life science research.

5-(2-Acetoxy-12-hydroxytridecyl)-1,3-benzenediol is a useful organic compound for research related to life sciences. The catalog number is T126037 and the CAS number is 133361-21-4.

Boc-MLF (TFA) is a specific antagonist of formyl peptide receptor (FPR) and also inhibits signaling through FPRL1 at higher concentrations.

Boc-D-Lys(2-Cl-Z)-OH, catalog number T66057 and CAS number 57096-11-4, is a valuable organic compound utilized in life sciences research.

11S,12-Dihydroxyspirovetiv-1(10)-en-2-one is a natural product for research related to life sciences. The catalog number is TN2594 and the CAS number is 62623-86-3.

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

Hydroxy-PEG1-(CH2)2-Boc is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].

Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).

Hydroxy-PEG3-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol, an endogenous triacylglycerol, comprises palmitic acid (at the sn-1 position), the fatty acid ester of hydroxy fatty acids (FAHFA), 12-PAHSA (at the sn-2 position), and oleic acid (at the sn-3 position). Identified in the lipid extract of mouse adipose tissue, this triacylglycerol demonstrates that levels of FAHFA-containing triacylglycerols are over 100-fold higher than those of non-esterified FAHFAs, suggesting their role as intracellular storage reservoirs for FAHFAs.