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By Target- Dehydrogenase
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Results for "
idh 305
" in TargetMol Product Catalog- Inhibitors & Agonists1
IDH-305
T155501628805-46-8
IDH-305 is an orally available, mutation-selective, and brain-penetrant IDH1 inhibitor targeting the IDH1 (R132) mutation. It is 200-fold more selective for mutant IDH1 isoforms than wild type, with IC50s of 27 nM, 28 nM, and 6.14 nM for IDH1R132H, IDH1R132C, and IDH1WT, respectively.
- $52
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