ilex

Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). Upon hydrolysis to candesartan during gastrointestinal absorption, it selectively competes with angiotensin II for binding to the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation.

Ilexsaponin B2 is a natural product for research related to life sciences. The catalog number is TJS0502 and the CAS number is 108906-69-0.

1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist.

Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.

1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.

Homovanillic acid (Vanillacetic acid), a dopamine metabolite, is linked to aromatic L-amino acid decarboxylase deficiency, growth hormone deficiency, celiac disease, and sepiapterin reductase deficiency.

Ilexhainanoside D is a natural product from Periploca sepiumBge.

Ilexgenin B is a natural product from Ilex chinensis Sims

Ilexoside XLVIII, a triterpene saponin isolated from the aqueous extract of Ilex kudincha leaves [1], functions as an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor.

Ilexgenin A is a novel pentacyclic triterpenoid, is a compound extracted from leaves of Ilex hainanensis Merr

Ilexoside O, a triterpene saponin derived from Ilex pubescens roots, demonstrates modest inhibition of xanthine oxidase (XOD) activity with an IC50 value of 53.05 μM.

Ilexoside K is a natural product from Ilex pubescens.

Trilexium (TRX-E-009-1), a third-generation benzopyran structurally related to TRX-E-002-1, increases p21 protein expression, induces apoptosis, depolymerizes microtubules, and demonstrates broad anti-cancer activity [1] [2].

Caulilexin C shows inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) and on human Acyl CoA: cholesterol transferase 2 (hACAT2) at 100 mug ml.

Brassilexin is a cyclobrassinin hydrolase inhibitor, a unique enzyme from the fungal pathogen Alternaria brassicicola.

Ilexside I is a useful organic compound for research related to life sciences and the catalog number is T124123.

Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.

Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities. Acetylursolic acid has inhibition against both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes.

Hederagenin-28-beta-D-glucopyranoside, a triterpenoid saponin isolated from Ilex cornuta, protects against H2O2-induced damage in cardiomyocytes.

Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).

Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.

5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound primarily found in the leaves of *Ilex glabra* L. Gray (Aquifoliaceae).

30-Oxolupeol is a natural product of Ilex, Aquifoliaceae. The catalog number is TN2985 and the CAS number is 64181-07-3. 30-Oxolupeol can be used as a reference standard.

Rotundanonic acid is a natural product from Ilex Rotunda.

Pedunculoside is extracted from Ilex rotunda Thunb.

Methyl 3,4-dihydroxyphenylacetate is a polyphenol found in I. aquifolium seeds, exhibiting antioxidant and antiviral activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 0.0025 mg ml) and inhibits enterovirus 71 replication in rhabdomyosarcoma cells (0.01 μg ml).

20-hydroxy Arachidic acid is a hydroxylated fatty acid that has been found in the suberin component of silver birch (B. pendula) outer bark as well as the leaves, roots, and wood of Q. ilex from Cala Violina and Colognole, Italy. 20-hydroxy Arachidic acid was identified as a potential inhibitor of human rhinovirus coat protein in a structure-based virtual screen.

Fraxiresinol 1-O-glucoside is a natural product from Ilex pubescens.

Randialic acid B shows significant cell-protective effects against H2O2-induced H9c2 cardiomyocyte injury.

22-Hydroxy docosanoic acid, a hydroxylated fatty acid identified within the suberin component of silver birch (B. pendula) outer bark, along with the leaves, roots, and wood of Q. ilex from Cala Violina and Colognole, Italy. [Matreya, LLC. Catalog No. 1818]