ingenol

1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV. 3. Ingenol is a weak PKC activator and possesses important anticancer activity.

Ingenol-5,20-acetonide-3-O-angelate (Ingenol 5,20-acetonide 3-angelate) is a natural product.

Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.

Ingenol-3,4,5,20-diacetonide, a natural product isolated from the sap of the Euphorbia plant, exhibits a wide range of biological activities, including anti-tumor, anti-inflammatory, and immunomodulatory effects.

Maltol is a type of aromatic compound found in high concentrations in red ginseng and is a potent antioxidant used to enhance flavor and preserve food.

Ingenol 3,20-dibenzoate is a powerful activator of protein kinase C (PKC) isoforms that effectively induces the translocation of nPKC-delta, -epsilon, and -theta, as well as PKC-mu, from the cytosolic fraction to the particulate fraction. Through de novo synthesis of macromolecules, it triggers apoptosis with characteristic morphology. Moreover, Ingenol 3,20-dibenzoate enhances IFN-γ production and degranulation in NK cells, particularly when stimulated by NSCLC cells[1][2].

3-O-(2'E,4'E-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124828.

Ingenol disoxate, also known as LEO43204, is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. Ingenol is a natural product found in the sap of the plant Euphor

Ingenol 20-palmitate is a natural product from Euphorbia sieboldiana.

3-O-(2'E,4'Z-Decadienoyl)ingenol, catalog number T124104, is a valuable organic compound for life sciences research.

Dodecanoic acid ingenol ester, a natural compound, shows moderate cytotoxicity with IC50 values being 35.59 μM (Caco-2), 24.04 μM (MCF-7), and 22.24 μM (MCF-7 ADM).

Ingenol-3-palmitate shows irritant and cocarcinogenic activity on mouse ear and on mice back skin.

3-O-(2'E,4'E-Decadienoyl)-ingenol is a naturally occurring diterpenoid compound exhibiting cytotoxicity towards the human normal cell lines L-O2 and GES-1, with half maximal inhibitory concentrations (IC50s) of 8.22 µM and 6.67 µM, respectively [1].

20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) is a natural compound found in the leaves and stems of the plant Inga. It has a variety of biological activities including tumor growth inhibition, anti-inflammatory, antifungal and antioxidant effects.

20-Deoxyingenol 3-angelate and ingenol 20-acetate 3-angelate are known as promoters of tumors of mouse skin. 20-Deoxyingenol 3-angelate can induce significant platelet aggregation accompanied by induction of phosphorylation of PKC substrates in platelets,

3-O-(2 ,3 -Dimethylbutanoyl)-13-O-decanoylingenol (compound 2) is a diterpene with antinematodal activity isolated from Euphorbia kansui.

20-DEOXYINGENOL is a natual product.

3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol is a useful organic compound for research related to life sciences and the catalog number is T124424.

3-O-(2'E,4'E-decadienoyl)-20-O-acetylingenol is an important organic compound for life sciences research [Catalog No. T124827, CAS No. 466663-12-7].

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol is a useful organic compound for research related to life sciences and the catalog number is T125709.

5-O-Benzoyl-20-deoxyingenol, a diterpene isolated from the roots of Euphorbia kansui, inhibits cell proliferation [1].