l67

L67 (DNA Ligase Inhibitor) is a competitive inhibitor of human DNA ligases I and III with an IC50 of 10 μM.

CL67 is a hypoxia-inducible factor pathway inhibitor. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro.

ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.

ARL67156 (FPL 67156) trisodium hydrate is a selective ecto-ATPase inhibitor and a competitive inhibitor of NTPDase1 (CD39), NTPDase3, and NPP1, with K i values of 11, 18, and 12 μM respectively. It is used in research of diseases such as calcific aortic valve disease and asthma [1] [2].

ARL67156 (FPL 67156) triethylamine, a selective ecto-ATPase inhibitor, functions as a competitive inhibitor for NTPDase1 (CD39), NTPDase3, and NPP1, exhibiting inhibition constants (Kis) of 11, 18, and 12 μM, respectively. This compound is applicable in researching diseases such as calcific aortic valve disease and asthma [1] [2].

ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels.

GL67 (N4-Spermine cholesteryl carbamate), a cationic lipid, facilitates the delivery of nucleic acid agents and vaccines, and is effective in gene transfection [1].