lc3 mhtt in an1

LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

Methyl 1-Cbz-azetidine-3-carboxylate acts as a stable ADC linker for synthesizing antibody-drug conjugates (ADCs) and as an alkyl chain-based PROTAC linker in developing PROTACs[1].

1-Boc-azetidine-3-yl-methanol [catalog number T66497, CAS number 142253-56-3] is a valuable organic compound for life sciences research.

1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs [1].

1-Boc-azetidine-3-carboxylic acid is a valuable organic compound for life sciences research (catalog number T67359, CAS number 142253-55-2).

PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD) with an IC50 of 0.6 nM and exhibits anti-proliferative activity.

1-Cbz-3-Hydroxyazetidine (catalog number: T66502, CAS number: 128117-22-6) is a valuable organic compound for life sciences research.

1-N-Boc-3-hydroxyazetidine (catalog number: T67084, CAS number: 141699-55-0) is a valuable organic compound used in life sciences research.

LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.

Methyl 1-Boc-azetidine-3-carboxylate, catalog number T66490 and CAS number 610791-05-4, is a valuable organic compound for life sciences research.

1-Cbz-azetidine-3-carboxylic acid (catalog number: T66609, CAS number: 97628-92-7) is a valuable organic compound for life sciences research.