m25

M 25 is a Smoothened (Smo) receptor antagonist.

M-25 is a Smoothened antagonist and inhibitor of the Hedgehog pathway.

Sonidegib metabolite M25 is a smoothened (SMO) antagonist.

AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 nM).

CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthosteric galanin binding site of the receptor (as measured by its inability to displace iodinated galanin, or to induce IP1 accumulation on its own).

δ receptor antagonist

TT15 is an agonist of the GLP-1R.