mal peg2 nhs

Mal-PEG2-NHS, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Mal-PEG2-NHS ester is a noncleavable antibody-drug conjugate linker containing a Maleimide moiety, a 2-unit PEG spacer, and an N-hydroxysuccinimide (NHS) ester functionality.

Mal-amido-PEG2-NHS ester is a noncleavable linker for antibody-drug conjugates (ADCs) that includes a maleimide group and an NHS ester, facilitating the labeling of protein primary amines (-NH2), amine-modified oligonucleotides, and other amine-containing molecules[1][2].

N-Mal-N-bis(PEG2-NHS ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester]

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and FGF21-receptor agonist, suitable for development as a potential treatment for T2DM.

Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker suitable for use in PROTAC synthesis [1].

Mal-PEG2-C2-Boc (Mal-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. Mal-PEG2-C2-Boc can be used in the synthesis of PROTACs.

Mal-PEG2-NH2 TFA is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Bis-PEG2-NHS ester, utilized in antibody-drug conjugation (ADC), functions as a non-cleavable linker with two polyethylene glycol (PEG) units.

m-PEG-mal (MW 20000) is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-mal (MW 2000) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

NHPI-PEG2-C2-NHS ester is a noncleavable two-unit polyethylene glycol (PEG) linker commonly used in antibody-drug conjugate (ADC) synthesis.

N-DBCO-N-bis(PEG2-C2-NHS ester) is a Polyethylene Glycol (PEG) derived linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Propargyl-PEG2-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-(PEG2-VC-PAB-MMAE)2 consists of Monomethyl auristatin E (MMAE), a potent tubulin inhibitor and toxin payload in antibody-drug conjugate [1], conjugated to the cleavable linker DBCO-(PEG2-VC-PAB)2, serving as the cytotoxic component in this formulation.

Mal-amido-PEG10-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that consists of a maleimide group and an N-hydroxysuccinimide (NHS) ester, which enables efficient labeling of primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules [1][2].

Mal-C2-NHS ester is a noncleavable linker compound commonly used in the synthesis of antibody-drug conjugates (ADCs)[1].

Mal-PEG3-NHS ester, a noncleavable ADC linker, possesses a Maleimide group. It serves as a crucial component in the synthesis of antibody-drug conjugates[1].

Mal-amido-PEG8-NHS ester, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Mal-amide-PEG2-oxyamineBoc is a polyethylene glycol (PEG)-based linker molecule with a Boc-protected oxyamine functionality, serving as an efficient and versatile tool for the synthesis of PROTACs (proteolysis targeting chimeras).

rm-PEG-NHS ester (MW 20000) is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1].

Tri(Mal-PEG2-amide)-amine, a polyethylene glycol (PEG)-derived linker, is commonly used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Mal-amido-PEG2-TFP ester is a polyethylene glycol (PEG)-based linker featuring amide functionality and a trifluorophenyl (TFP) ester group, used in PROTAC synthesis as a PEG-based PROTAC linker [1].

N-Mal-N-bis(PEG2-acid) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system in cells.

endo-BCN-PEG2-C2-NHS ester is a PEG-based linker for PROTACs that connects two critical ligands, essential for the formation of PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

DBCO-(PEG2-Val-Cit-PAB)2 is a dual-cleavable linker used in antibody-drug conjugates (ADCs).

N-Mal-N-bis(PEG2-C2-Boc) is a polyethylene glycol (PEG)-based linker used in proteolysis targeting chimeras (PROTACs)[1].

m-PEG-mal (MW 10000) is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-O-C1-amido-PEG2-C2-NHS ester is a non-cleavable 2-unit PEG linker used in antibody-drug conjugation (ADC) to connect antibodies with drugs.

Mal-PEG12-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Fmoc-PEG2-CH2CH2-NHS ester is a polyethylene glycol (PEG)-based linker constructed for the synthesis of proteolysis targeting chimeras (PROTACs).

m-PEG-Lys-NHS ester (MW 40000) is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs [1].

Mal-PEG2-oxyamine, a PEG-based linker for PROTACs, connects two essential ligands and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable, 2-unit polyethylene glycol (PEG) based ADC linker used in the construction of antibody-drug conjugates (ADCs) [1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker, incorporating a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for PROTAC technology applications.

The PEG-based PROTAC linker, N-(Azido-PEG2)-N-Boc-PEG3-NHS ester, is suitable for the synthesis of PROTACs[1].

N-(Azido-PEG2)-N-Boc-PEG4-NHS ester, a PEG-based PROTAC linker, facilitates PROTAC synthesis [1].

Mal-amido-PEG9-NHS ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system [within cells].

m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Mal-PEG4-NHS ester is a noncleavable ADC linker with a Maleimide group, a 4-unit PEG, and an NHS ester.

N3-PEG2-C2-NHS ester is a noncleavable, two-unit PEG linker designed for the synthesis of antibody-drug conjugates (ADCs).

Mal-PEG2-VCP-NB is a noncleavable ADC linker comprising a Maleimide group, a 2-unit PEG, and a VCP NB.

3,4-Dibromo-Mal-PEG2-N-Boc is a PEGylated PROTAC linker used in PROTAC synthesis [1].

Mal-PEG-mal (MW 2000) is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It can be conjugated to Tubulysin and its derivative cytotoxic molecule [1].