n-3-c3-nhs ester

N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

N3-C4-NHS ester, a non-cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).

Azido-PEG12-NHS ester, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

AP1867-3-(aminoethoxy) is a synthetic ligand for FKBP and can be used in the synthesis of PROTAC FKBP12 F36V degrader.

Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-derived linker used for PROTAC synthesis.

Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) is a nonclaevable linker used for antibody-drug-conjugation (ADC).

Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.

Ald-Ph-NHS ester is a non-cleavable linker utilized in antibody-drug conjugation (ADC).

Boc-NH-O-C1-NHS ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

N3-Ph-NHS ester is a noncleavable ADC linker that can be utilized in the synthesis of antibody-drug conjugates (ADCs).

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

Fmoc-PEG12-NHS ester, a PEG-based linker for PROTACs, facilitates the joining of two essential ligands, crucial for the formation of PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker employed in PROTAC synthesis [1].

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester]

m-PEG24-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker suitable for use in PROTAC synthesis [1].

N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a polyethylene glycol (PEG) based PROTAC linker used for PROTAC synthesis[1].

SPDP-PEG4-NHS ester is a PEG-based linker for PROTACs that connects two essential ligands necessary for forming PROTAC molecules, facilitating selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

LL-K9-3, a selective hydrophobic tagging technology (HyT)-based degrader, specifically targets the CDK9-cyclin T1 complex, displaying DC50 values of 589 nM for cyclin T1 and 662 nM for CDK9. This compound consists of the CDK9 inhibitor, SNS 032, linked to a hydrophobic tag via a glycol linker. Notably, LL-K9-3 does not affect the degradation of other CDKs (CDK1, 2, 4, 5, 6, and 7). Tested in 22RV1 cells, it effectively reduces androgen receptor (AR) and cMyc expression by inducing the selective and synchronous degradation of CDK9 and cyclin T1.

3-Mercaptopropionic acid NHS ester is a useful organic compound for research related to life sciences and the catalog number is T64663.

Mal-PEG5-NHS ester, an alkyl ether and PEG-based PROTAC linker, is utilized for the synthesis of PROTACs.

Mal-amido-PEG6-NHS ester, a polyethylene glycol (PEG)-based linker, is specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Biotin-PEG12-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs.

Boc-N-PEG1-C2-NHS ester, a PEG-based linker, finds utility in PROTAC synthesis[1].

Fmoc-PEG6-NHS ester is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Methyl 3-hydroxypropanoate is a PROTAC linker compound, which belongs to the alkyl ether family. It is commonly employed in the synthesis of PROTACs.

N-Boc-N-bis(PEG3-NHS ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

SPDP-PEG24-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules for selective protein degradation via the ubiquitin-proteasome system within cells.

N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is an alkyl ether-based linker for PROTACs, facilitating the connection of two essential ligands critical for forming PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Tetrazine-Ph-PEG5-NHS ester is a PEGylated N-hydroxysuccinimide (NHS) ester molecule utilized as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

PROTAC BET Degrader-3 is a potent degrader of BET proteins based on the PROTAC (PROteolysis TArgeting Chimera) technology.

m-PEG6-NHS ester is a non-cleavable PEG linker consisting of 5 units, employed in the synthesis of antibody-drug conjugates (ADCs).

Biotin-C5-NHS Ester is an alkyl ether-based linker used in PROTAC synthesis [1].

Iodo-PEG12-NHS ester is a PEG-based linker for PROTACs that connects two key ligands, essential for the formation of PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Azido-PEG1-NHS ester is a PEG-based linker for PROTACs, enabling the formation of PROTAC molecules by joining two essential ligands and facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Mal-amido-PEG10-C2-NHS ester is a noncleavable ADC linker with a maleimide group and an NHS ester, used as a labeling agent for primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules [1][2].

PROTAC SOS1 Degrader-3 is a potent agent specifically designed to target and degrade SOS1 via the ubiquitin-proteasome system [1].

DBCO-NHCO-S-S-NHS ester is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Boc-NH-PEG2-C2-NHS ester is an alkyl ether-derived PROTAC linker used in the synthesis of PROTACs [1].

DBCO-NHCO-C4-NHS ester, an alkyl chain-derived PROTAC linker, is used for PROTAC synthesis[1].

m-PEG2-O-Ph-3-NH2 is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Acid-C2-PEG3-NHS ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG8-ethoxycarbonyl-NHS ester is a polyethylene glycol (PEG)-based linker, utilized for the synthesis of PROTACs. It serves as an effective coupling agent, facilitating the conjugation of two molecules within PROTACs. This compound offers a stable and efficient platform for the delivery of targeted protein degradation therapeutics. [1]

Biotin-PEG4-NHS ester, a biotinylated and PEGylated N-hydroxysuccinimide ester, serves as a linker in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

PPC-NHS ester, a cleavable linker crucial in ADC synthesis, facilitates the attachment of cytotoxic drugs to antibodies for precise delivery to cells or proteins. Its cleavable nature ensures controlled drug release, thereby optimizing the effectiveness of ADCs (Antibody-Drug Conjugates).

Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable triethylene glycol linker featuring propargyl and N-hydroxysuccinimide (NHS) functional groups, used in the synthesis of antibody-drug conjugates (ADCs)[1].