n6isopentenyladenosine

N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea is a cinchona alkaloid-derived bifunctional catalyst.

(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.

N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform N-terminal biotinylation.

Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.

N-(2-chloro-3-((3,5-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)oxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanesulfonamide is a useful organic compound for research in chemistry and life sciences.

N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine functions as an inhibitor of the PAICS protein, effectively decreasing the accumulation of both SAICAR and SAICAr.

Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities.

A natural compound from the herbs of Aristolochia debilis Sieb. et Zucc

5-n-Heptyl-6-hydroxy-4,7-dioxobenzothiazole acts as a competitive inhibitor at the Qo site of the cytochrome bc1 complex (cytochrome c oxidoreductase) in Saccharomyces cerevisiae [1].

N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T65343 and the CAS number is 231278-20-9.

N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T64879 and the CAS number is 162012-67-1.

2’-C-Methyl nucleoside; Halo-nucleoside; 2/6/8-Modified purine nucleoside

Heterocyclic Compounds - Fused polyheterocycles; Drugs and Inhibitors; Anticancer agent

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.

N-[5-[[[3-(6-Amino-4-methylpyridin-3-yl)-1-methyl-1H-indazol-5-yl]carbonyl]amino]-2-methylphenyl]-N′-methylterephthalamide had an IC50 value of 22 nM in a BD2 DEC-Tec assay.

(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide is a useful organic compound for research related to life sciences. The catalog number is T66342 and the CAS number is 863127-76-8.

9-Methoxycanthin-6-one-N-oxide shows cytotoxic activity against a panel of cell lines comprising a number of human cancer cell types.

(S)-N-(2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)propionamide is a useful organic compound for research related to life sciences. The catalog number is T65667 and the CAS number is 106006-84-2.

N-((2R,3R,4R,5R)-5,6-Dihydroxy-1-oxo-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)hexan-2-yl)acetamide is a natural product for research related to life sciences. The catalog number is T65274 and the CAS number is 71208-06-5.

4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).

6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin A is a useful organic compound for research related to life sciences and the catalog number is T64488.

N-[5-Bromomethyl-4-(4-fluorophenyl)-6-isopropylpyrimidine-2-yl]-N-methylmethane sulfonamide is a useful organic compound for research related to life sciences. The catalog number is T66071 and the CAS number is 799842-07-2.

N-[5-[[[3-(6-Amino-2-methylpyridin-3-yl)-1-methyl-1H-indazol-5-yl]carbonyl]amino]-2-methylphenyl]-N′-methylterephthalamide had an IC50 value of 94 nM in a BD2 DEC-Tec assay.

N-((2S,3R,4R,5S,6R)-2-(((2R,3S,4S,5R,6S)-3,5-Dihydroxy-2-(hydroxymethyl)-6-(((2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-5-hydroxy-6-(hydroxymethyl)-4-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)acetamide has a wide range of applications in life science related research.

(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T66550 and the CAS number is 314771-88-5.

N1-(tert-Butoxycarbonylmethyl)-6-[2-(N-Cbz-amino)ethoxy)]-phenoxazine is a PNA-related Derivative; Heterocyclic Compound - Fused polyheterocycle.

N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide is a useful organic compound for research related to life sciences. The catalog number is T65333 and the CAS number is 848133-76-6.

4-Fluoro-N-(6-nitrobenzo[d]thiazol-2-yl)benzamide is a Heterocyclic Compound and can be used in anticancer and antimicrobial studies.

tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is a useful organic compound for research related to life sciences. The catalog number is T66277 and the CAS number is 289042-12-2.

N-6-Furfurylguanosine is a 2/6/8-modified purine nucleoside.

N-(4-(4-Fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T65584 and the CAS number is 147118-37-4.

Wnt signaling is required for direct multiple biological processes and also plays key roles in the pathogenesis of various diseases. Cyclic AMP response element-binding protein (CREB) is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Via generating a transcriptionally active complex with β-catenin, CREB acts as a mediator of Wnt signaling.ICG-001 is an inhibitor of β-catenin/CREB mediated transcription. The direct cellular target of ICG-001 is CREB. the inhibitory IC50of ICG-001 against β-catenin/CREB mediated transcription was 3 μM. ICG-001 treatment at the concentration of 25 μM for 24h significantly increased caspase activity in both colon cancer cell lines SW480 and HCT116 cell lines but not in normal colonic epithelial cells CCD-841Co. In a cell growth inhibition assay, the IC50s of ICG-001 against SW480 and HCT116 cells were 4.43 μM and 5.95 μM, respectively.In a SW620 nude mouse xenograft model, an water-soluble analog of ICG-001 given at the dose of 150 mg/kg i.v. once in every 2 days dramatically suppressed tumor growth. In a bleomycin-induced pulmonary fibrosis mice model, ICG-001 given at the dose of 5 mg/kg per day reversed pulmonary fibrosis. In a rat myocardial infarction model, ICG-001 was administrated subcutaneously at the dose of 50 mg/kg/day for 10 days which significantly improved cardiac contractile function after myocardial infarction in the rats.

N-(5-(8-Amino-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-2-methylphenyl)methanesulfonamide hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64837.

2-Acetylamino-1-{3’-O-[(4,4’-dimethoxy triphenyl)methyl]-a-L-threo furanosyl}-6-(N,N-diphenylcarbamoyloxy)-9H-purine is a nucleoside analog and has a wide range of applications in life science related research.

N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64522.

N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T66148 and the CAS number is 289042-10-0.

tert-Butyl N-[6-(methylamino)hexyl]carbamate is a useful organic compound for research related to life sciences and the catalog number is T64467.

6-Acetonyl- N -methyl-dihydrodecarine has mosquito larvicidal activity against the malaria vector Anopheles gambiae.

N1-Carboxymethyl-6-[2-(N,N'-bis-Cbz-guanidino) ethoxy]-phenoxazine is a PNA-related Derivative; Heterocyclic Compound - Fused polyheterocycle.

N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/differentiation and improves the efficiency