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Results for "
nexinhib-20
" in TargetMol Product Catalog- Inhibitor Products2
Nexinhib20
T38384331949-35-0
Nexinhib20 is an inhibitor of the protein-protein interaction between the small GTPase Rab27a and its effector JFC1 (IC50 = 2.6 μM).[1] It inhibits myeloperoxidase (MPO) secretion induced by granulocyte macrophage colony-stimulating factor (GM-CSF) and fMLP in isolated human neutrophils (IC50 = 0.33 μM). Nexinhib20 (30 mg/kg) reduces LPS-induced increases in plasma MPO levels, as well as LPS-induced hepatic and renal neutrophil infiltration in a mouse model of endotoxin-induced systemic inflammation.
- $78
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QTY
(Z)-Nexinhib20
T777661162656-24-7
(Z)-Nexinhib20 is a biochemical reagent that can be used in biological experiments.
- $195
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