Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions.

Pitavastatin D4 is deuterium labeled Pitavastatin. Pitavastatin is a potent inhibitor of HMG-CoA reductase.

Pitavastatin (NK-104) is a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor with hypocholesterolemic and neuroprotective activities, inhibits synthesis of cholesterol from acetic acid, and reduces oxidative stress.Pitavastatin is a hepatocellular low-density lipoprotein cholesterol (LDL-C) receptor inducer, and may be used to Pitavastatin is a hepatocellular LDL-C receptor inducer and is used in the study of coronary atherosclerosis, hypercholesterolemia, and acute coronary syndromes.Pitavastatin is structurally unstable and is recommended to be formulated for immediate use.

Pitavastatin-d4 Sodium Salt is a deuterated compound of Pitavastatin Sodium Salt. Pitavastatin Sodium Salt has a CAS number of 574705-92-3. Pitavastatin (NK-104) sodium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin sodium inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin sodium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin sodium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8].

Pitavastatin (NK-104) sodium is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and a potent inducer of the hepatocyte low-density lipoprotein cholesterol (LDL-C) receptor. pitavastatin sodium inhibits acetate synthesis of cholesterol in HepG2 cells ( Pitavastatin sodium exhibits anti-atherogenic, anti-osteoarthritic, anti-asthmatic, anti-tumour, neuroprotective, hepatoprotective and nephroprotective effects.