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nov120101 hydrochloride

" in TargetMol Product Catalog

Inhibitors & Agonists
2

Poziotinib hydrochloride

T87581429757-68-5

Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.

EGFR

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Poziotinib

T26301092364-38-9

Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).

Apoptosis EGFR HER

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