oxacillin

Oxacillin is an orally active synthetic penicillin that exhibits effective bactericidal activity against staphylococci and other gram-positive pathogens.

Oxacillin sodium salt (Oxabel) is an antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.

Oxacillin sodium monohydrate (Stapenor monohydrate) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.

Cloxacillin sodium monohydrate (Cloxacillin Sodium) is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.

Flucloxacillin sodium (floxacillin sodium) is a highly active antibiotic against Gram-negative and Gram-positive bacteria.

Dicloxacillin Sodium hydrate is a narrow-spectrum β-Lactam antibiotic of the penicillin class, used to treat infections caused by susceptible Gram-positive bacteria.

Cloxacillin Sodium, a chlorinated derivative of Oxacillin, is a semi-synthetic antibiotic. Cloxacillin is used for the treatment of infections caused by species of staphylococci which produce beta-lactamase.

Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive negative aerobic and anaerobic bacteria.

Dicloxacillin (INN), a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins.

Flucloxacillin, an antibiotic, effectively combats both gram-positive and gram-negative bacteria [1] [2].

Cloxacillin, an orally active antibacterial agent and β-lactamase inhibitor, exhibits an IC50 of 0.04 µM. It effectively suppresses S. aureus-induced inflammatory responses by inhibiting the activation of MAPKs, NF-кB, and NLRP3-related proteins.

TunR2 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtiliswhen used at a concentration of 0.4 μg/ml. Unlike tunicamycin, TunR2 is non-toxic toS. cerevisiae(MIC = >10 μg/ml) and does not inhibit glycosylation in a protein N-glycosylation assay. TunR2 also has reduced antiproliferative activity against MDA-MB-231 and CHO cells compared with tunicamycin. 1.Price, N.P., Hartman, T.M., Li, J., et al.Modified tunicamycins with reduced eukaryotic toxicity that enhance the antibacterial activity of β-lactamsJ. Antibiot. (Tokyo)70(11)1070-1077(2017)

TunR1 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtiliswhen used at a concentration of 0.4 μg/ml. TunR1 (5 μg/ml) is cytotoxic to MDA-MB-231 breast cancer cells and non-cancerous CHO cells. Unlike tunicamycin, TunR1 does not inhibit glycosylation in a protein N-glycosylation assay. 1.Price, N.P., Hartman, T.M., Li, J., et al.Modified tunicamycins with reduced eukaryotic toxicity that enhance the antibacterial activity of β-lactamsJ. Antibiot. (Tokyo)70(11)1070-1077(2017)