p-nitro-pifithrin-alpha

Pifithrin-α, p-Nitro, Cyclic (PFN-α) (PFN-α) is cell-permeable and active-form inhibitor of p53.

p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor. It suppresses p53-mediated TGF-β1 expression in HK-2 cells and inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. Moreover, p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice subjected to a high-fat diet, mitigating the effects of non-alcoholic fatty liver disease [1] [2] [3] [4].

m-Toluidine, alpha-((p-chlorophenyl)sulfonyl)-4-(octyloxy)- is a bioactive chemical.

p-Phenetidine, 3-methoxy-alpha-phenoxy- is a Drug / Therapeutic Agent.

m-Toluidine, 4-(octyloxy)-alpha-(p-tolylsulfonyl)- is a bioactive chemical.

m-Cresol, alpha,alpha,alpha-trifluoro-6-nitro-, p-nitrobenzoate is a bioactive chemical.

Phthalimide, N-(5-(p-aminophenoxy)pentyl)-3-nitro- is a bioactive chemical.

Cinnamic acid, m-chloro-alpha-methyl-, 7-nitro-8-quinolyl ester is a bioactive chemical.

H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide capable of acting as a substrate for enzymes cathepsin D, pepsin, and pepsinogen, holding potential applications in biochemical analysis [1] [2].