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(2)
By Target- Acyltransferase
- Transferase(2)
- c-Met/HGFR(1)
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Results for "
pf06424439 methanesulfonate
" in TargetMol Product Catalog- Inhibitors & Agonists3
PF-06424439 methanesulfonate
T124251469284-79-4
PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM, demonstrates slow reversibility and time-dependent inhibition. It operates in a noncompetitive manner relative to the acyl-CoA substrate, marking its efficacy in targeting DGAT2.
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PF-04217903 methanesulfonate
T12417956906-93-7
PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).
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PF-06424439
T124261469284-78-3
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
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