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pha 543613 hydrochloride

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  • Inhibitors & Agonists
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PHA 543613 hydrochloride
T704201586767-92-1
PHA-543613 hydrochloride acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.
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1-2 weeks
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PHA 543613
T23145478149-53-0In house
PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.
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6-8 weeks
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PHA-767491 hydrochloride
CAY10572,PHA-767491,PHA767491 HCl,CAY-10572 hydrochloride
T6940942425-68-5
PHA-767491 hydrochloride (CAY-10572 hydrochloride) is an effective ATP-competitive dual Cdc7 CDK9 inhibitor (IC50: 10 34 nM). It has ~20-fold selectivity against GSK3-β and CDK1 2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
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Clamikalant
T71929158751-64-5
Clamikalant inhibits ATP-sensitive potassium channel.
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6-8 weeks
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