pi3k in 19 hydrochloride

PI3K-IN-19 hydrochloride (WO2017153220, step 5) acts as a phosphatidylinositol-3-kinase (PI3K) inhibitor.

Methyl 3-aminopropanoate hydrochloride (β-Alanine methyl ester hydrochloride) is the ethyl ester of the non-essential amino acid β-alanine.

3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human brain and most tissues tissues; and in blood, cerebrospinal fluid (csf) or urine. Within a cell, 3-methoxytyramine is primarily located in the cytoplasm.

N-Nornuciferine hydrochloride(4846-19-9 free base) (N-Nornuciferine hydrochloride) is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).

BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.

3-(2-aminopropyl)phenol hydrochloride is a phenethylamine analog used as a molecular structural unit. It is a psychoactive drug that is a partial agonist at several serotonin receptors, including 5-HT1A, 5-HT1B, and 5-HT2C, as well as an antagonist at the 5-HT2A receptor.

WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.

VA-K-14 hydrochloride（VAK14 HCl） is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.

ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.

A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively[1], and also inhibits PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM), and myosin light chain kinase (MLCK) (Ki=7.4 μM).

NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0 G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).

(2R,3S)-3-Phenylisoserine hydrochloride serves as a pharmaceutical intermediate.

3-Pyridylacetic acid hydrochloride (3-PAA-HCl) is a high homologue of niacin. It is a decomposition product of nicotine (and other tobacco alkaloids). It can also react with amines, alcohols and carboxylic acids, and can also act as an acid in the reaction. catalyst.

4-Hydroxy-3-methoxybenzylamine hydrochloride (N-Vanillylamine hydrochloride) is an alkaloid that is an intermediate in the biosynthesis of capsaicin. 4-Hydroxy-3-methoxybenzylamine hydrochloride is produced from vanillin by the enzyme vanillin aminotransferase.

(S)-3-Amino-1-chloro-5-methylhexan-2-one hydrochloride [catalog number T65276, CAS number 54518-92-2] is a valuable organic compound for life sciences research.

(S)-Methyl 2-amino-3-cyclohexylpropanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66551 and the CAS number is 17193-39-4.

2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride is a valuable organic compound for life sciences research. [Catalog number: T64780, CAS number: 4876-14-6].

(S)-3-Aminohexanedioic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66088 and the CAS number is 61884-74-0.

3-(Chloromethyl)pyridine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66829 and the CAS number is 6959-48-4.

2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67443 and the CAS number is 127337-60-4.

(S)-4-(Amino(carboxy)methyl)-3-methylbenzoic acid hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64800.

3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66115 and the CAS number is 5409-58-5.

3-Aminobutanenitrile hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64404 and the CAS number is 50840-31-8.

3-Nitro-L-tyrosine ethyl ester hydrochloride [catalog number T124433] is a valuable compound for life sciences research.

NAMPT inhibitor

2-(Benzyl(methyl)amino)-1-(3-hydroxyphenyl)ethanone hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65560 and the CAS number is 71786-67-9.

3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart rate, and cardiac output. It has also been reported to function in controlling lipid and glucose utilization, hormonal secretion, and neuronal function, and has been considered for use in chemically-induced hibernation for medical purposes.

Ethyl azetidine-3-carboxylate hydrochloride [Catalog No. T65152, CAS No. 405090-31-5] is a valuable organic compound for life sciences research.

Methyl azetidine-3-carboxylate hydrochloride is a valuable organic compound for life sciences research (catalog number: T65646, CAS number: 100202-39-9).

(1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride dihydrate is a useful organic compound for research related to life sciences and the catalog number is T64506.

PI3K mTOR Inhibitor-3 (compound 12) is an imidazoline compound with potent dual inhibition of PI3K and mTOR, exhibiting notable anti-cancer activity [1].

Phenol, m-(1,3-dimethyl-3-pyrrolidinyl)-, acetate, hydrochloride is a bioactive chemical.

Intermediates and Building Blocks - Nucleophiles; Component: 13822-06-5

Methyl 2-amino-3-chloropropanoate hydrochloride [Catalog No. T67646, CAS No. 33646-31-0] is a valuable organic compound for life sciences research.

(2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. This compound can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules that contain an alkyne group. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules featuring DBCO or BCN groups.

(S)-Methyl 2-amino-3-(3-hydroxyphenyl)propanoate hydrochloride, with catalog number T66437 and CAS number 34260-72-5, is a valuable organic compound for life science research.

(S)-2-Amino-3-hydroxypropanamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66126 and the CAS number is 65414-74-6.

(S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride is a valuable organic compound for life sciences research [Catalog Number: T66364, CAS Number: 181228-33-1].

Stevia impurity (13-[(2-O-6-deoxy-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester) is a natural product for research related to life sciences. The catalog number is TN6498 and the CAS number is 1309929-72-3.

(S)-Benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride is a valuable organic compound for life sciences research (Catalog No. T66692, CAS No. 1194550-59-8).

(S)-tert-Butyl 2-amino-3-methylbutanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65726 and the CAS number is 13518-40-6.

Propyl (3-(dimethylamino)propyl)carbamate hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T65408.

(S)-2-Amino-3-(2-hydroxyphenyl)propanoic acid hydrochloride is a valuable organic compound for life sciences research [Catalog No. T66634, CAS No. 1810074-88-4].

N-(3-Fluorophenyl)piperidin-4-amine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67608 and the CAS number is 923565-91-7.

(R)-Benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67333 and the CAS number is 2049127-88-8.

3-Piperazinobenzisothiazole hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65208 and the CAS number is 87691-88-1.

(S)-Methyl 3-([1,1'-biphenyl]-4-yl)-2-aminopropanoate hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T65310.

N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)furan-2-carboxamide hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T66667.