pi4kiiib-in-10

Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].

Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).

Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC50 of 42.0 μM.

Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .

[bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist.

Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .

Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds in the transmembrane domain of the κ-receptor.

(β-Ala8)-Neurokinin A (4-10), a neuropeptide, acts as a potent and selective agonist for the NK-2 tachykinin receptor [1].

[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a potent and highly selective NK2 receptor agonist, exhibiting an IC50 value of 6.1 nM [1].

Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in mice. This peptide does not elicit an inflammatory response.

Neurokinin A (4-10) TFA is a tachykinin NK 2 receptor agonist [1] .

Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect in rat models [1] [2].

(p-Iodo-Phe7)-ACTH (4-10), a derivative of adrenocorticotrophic hormone (ACTH) produced by the anterior pituitary gland, functions as a melanocortin (MC) receptor antagonist. It effectively inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats [1].

[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA), a Neurokinin A analogue, serves as a selective and potent agonist for the NK2 receptor (NK2R). This compound exhibits prokinetic activity, making it a valuable tool for researching smooth muscle contraction across various tissues through NK-2 receptor engagement [1] [2] [3].

(Trp7,β-Ala8)-Neurokinin A (4-10) is a potent neurokinin-3 (NK3) antagonist [1] .

Saralasin acetate is a Non-selective angiotensin II antagonist.

LH-RH (4-10), a heptapeptide, represents one of the primary degradation products of luteinising-hormone releasing hormone (LHRH), occurring through the pathways of the pituitary and hypothalamus. It is produced in macrophages and type II pneumocytes [1].

Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2. Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in th