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(1)
By Target- Porcupine
- Wnt/beta-catenin(1)
- Others(1)
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Results for "
porcn-in-1
" in TargetMol Product Catalog- Inhibitors & Agonists3
Porcn-IN-1
Cited
Porcupine-IN-1
T44382036044-77-4
Porcn-IN-1 (Porcupine-IN-1) is an effective porcupine inhibitor (IC50: 0.5±0.2 nM).
Inquiry
CitedIWP-3
T21650687561-60-0
IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].
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Porcn-IN-2
T798101900754-65-5
Porcn-IN-2 (Example 107) is a potent Wnt pathway inhibitor with an IC50 of 0.05 nM, applicable in cancer research including sarcoma, melanoma, skin cancer, hematological tumors, lymphoma, carcinoma, and leukemia [1].
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