saikosaponin

1. Buddlejasaponin IVb (Saikosaponin 1b)(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy.

Saikosaponin F is a natural compound found in Bupleurum (B.) falcatum L.

Saikosaponin B4 is isolated from the MeOH extract of the roots of Bupleurum falcatum L.

Saikosaponin b3 is isolated from the roots of Bupleurum falcatum L.. Saikosaponin b3 inhibits ACTH-induced lipolysis in the fat cells and exhibits analgesic effects.

Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.

Saikosaponin H is a natural product from Bupleurum chinense.

Saikosaponin G is a natural product

Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with potentiation of expressions of tyr

Saikosaponin E is a natural product isolated from the herbs of Bupleurum.

Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.

Saikosaponin I shows strong inhibition activity against influenza virus WSN33.

Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38 MAPK and NF-κB signaling pathways in spinal cord. It can inhibit NMDA receptor current and persistent sodium current, and inhibit the TNF-α level, the IL-1β production, and cysteine-aspartic acid protease (caspase)-1 activity.

Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.

Saikosaponin S, a natural compound, is isolated from Bupleurum scorzonerifolium [1].

Nepasaikosaponin K is a small molecule compound isolated from Chaikosaponin root with anti-influenza and antiviral activity and can be used in the study of viral infections.

11(α)-Hydroxynepasaikosaponin K (HOSSc) is a saikosaponin derived from Bupleurum scorzonerifolium Willd [1].

6''-O-acetylsaikosaponin A is an acetyl saikosaponin isolated from the roots of Bupleurum chinense. Itshows some osteoclast-inhibiting activities

6′′-O-Acetylsaikosaponin b2 (compound 11), a natural saikosaponin, is identified in Bupleurum chinense [1].

6″-O-Acetylsaikosaponin b3 is a natural product for research related to life sciences. The catalog number is TN5968 and the CAS number is 104109-34-4.

Tibesaikosaponin V (TKV), a triterpene diglycoside isolated from the methanol extract of Bupleurum chinense DC roots, effectively inhibits lipid accumulation and triacylglycerol content in adipocytes without inducing cytotoxicity. It suppresses mRNA expression of nuclear transcription factors, including peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα), and impedes 3T3-L1 preadipocyte differentiation. Considering these properties, Tibesaikosaponin V is a promising compound for researching obesity and related metabolic disorders [1].

6''-O-Acetylsaikosaponin D is a natural product for research related to life sciences. The catalog number is TN2968 and the CAS number is 64340-45-0.

11alpha-Methoxysaikosaponin F is a natural product

Hydroxysaikosaponin C, a natural extract from Bupleurum falcatum roots, exhibits potent biological activity [1].

2''-O-acetylsaikosaponin A is a natural product for research related to life sciences. The catalog number is TN2781 and the CAS number is 102934-42-9.

Prosaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial

Prosaikogenin H, an intestinal metabolite derived from saikosaponin, exhibits weak hemolytic activity.