schisandrin a

Schisandrin C epoxide is a natural product for research related to life sciences. The catalog number is TN4958 and the CAS number is 81345-36-0.

Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.

1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation.

Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.

Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.

Schisandrin A, a primary active component extracted from the traditional Eastern medicine Schisandra chinensis, inhibits CYP3A activity, with an IC50 of 6.60 μM and a Ki of 5.83 μM.

Changnanic acid (schisandrin), a triterpene compound, has demonstrated potential anti-tumor properties, exhibiting moderate cytotoxicity against human tumor cell lines Bel-7402 and MCF-7 with IC50s of 100 μM, and against HL-60 with an IC50 of 50.51 μM [1].

Schisandrin E (compound 5), a lignan extractible from Schisandra chinensis [1], exhibits pharmacological properties.

Schisandrin C, a lignan extracted from the fruit of Schisandra chinensis, exhibits antihepatitis, antitumor, and anti-HIV-1 activities [1].