senecionine

Cytidine 5'-triphosphate disodium salt is one of the endogenous metabolites and is a cation-permeable ligand-gated ion channel agonist.

Senecionine n-oxide is a major product of pyrrolizidine nucleic alkaloid biosynthesis in unusual root cultures of Trichoderma lucidum.Senecionine N-oxide (Senecionine oxide) has antitumor activity but induces hepatic sinusoidal obstruction syndrome.Senecionine n-oxide acts as a chelating tracer for N-oxide.

Senecionine acetate (O-Acetylsenecionine), a pyrrolizidine alkaloid, inhibits the sequestration of Ca2+ in both extramitochondrial and mitochondrial compartments, likely through the inactivation of free sulfhydryl groups [1].

Seneciphylline N-oxide is a pyrrolizidine alkaloid obtained from Emilia sonchifolia and is the dehydrogenation product of Senecionine N-oxide.