suberoyl bis-hydroxamic acid

Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on the N-terminal of the core histones.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

3,5-Bis(4-nitrophenoxy)benzoic acid (Compound W) is a γ-secretase inhibitor that reduces the levels of released Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).

Bis(2-methylpropyl)phosphinodithioic acid is a bioactive chemical.

Bis-PEG10-acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-Mal-Lysine-PEG4-acid is a PEG-based PROTAC linker used for PROTAC synthesis [1].

Bis-PEG13-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-(m-PEG4)-amidohexanoic acid is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Bis-CH2-PEG2-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker extensively used in the synthesis of PROTACs (proteolysis targeting chimeras)[1].

Bis-(m-PEG8-amido)-hexanoic acid is a polyethylene glycol (PEG)-based linker used in synthesizing proteolysis targeting chimeras (PROTACs) [1].

(S)-2,3-Bis((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid is a valuable organic compound for life sciences research, catalog number T66729 and CAS number 201473-90-7.

2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid is a valuable organic compound for life sciences research [Catalog number: T66395, CAS number: 171557-31-6].

N-(Biotin-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker molecule used in the synthesis of PROTACs[1].

PEG4-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative functioning as a linker in PROTAC synthesis, specifically designed for creating proteolysis-targeting chimeras (PROTACs)[1].

N-Me-N-bis(PEG4-acid) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Bis-PEG4-sulfonic acid is a PEG-based linker for PROTACs, facilitating the conjugation of essential ligands critical for PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Phthalic acid, bis-isobutyl ester-d4 is a deuterated compound of Phthalic acid, bis-isobutyl ester. Phthalic acid, bis-isobutyl ester has a CAS number of 84-69-5. Dibutyl phthalate is a plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.

Bis(p-chlorophenyl)acetic acid is a standard for pesticide residue analysis.

N-(Propanoic acid)-N-bis(m-PEG12) is a polyethylene glycol (PEG) based linker used in PROTACs synthesis [1].

PEG2-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative frequently used as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Bis-PEG12-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-N-bis(PEG4-C2-acid) is a polyethylene glycol (PEG) derivative used as a PEG-based PROTAC linker for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

N-(Amino-PEG3)-N-bis(PEG3-acid) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Bis-PEG14-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

N-(Azido-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker, facilitating PROTAC synthesis [1].

N-DBCO-N-bis(PEG2-C2-acid) is a polyethylene glycol (PEG) linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

PEG2-bis(phosphonic acid) is a PEG Linker.

N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Bis-PEG4-acid is a PEG PROTAC linker (PROteolysis TArgeting Chimera) used in targeted protein degradation applications.

Bis-PEG25-acid, a PEG-based linker for PROTACs, joins two essential ligands for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Phthalic acid, bis-propyl ester-d4 is a deuterated compound of Phthalic acid, bis-propyl ester. Phthalic acid, bis-propyl ester has a CAS number of 131-16-8.

m-((4-((4-(Bis(2-hydroxyethyl)amino)phenyl)azo)-1-naphthyl)azo)benzenesulphonic acid is a bioactive chemical.

PEG3-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative linker designed for use in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-based linker compound intended for the synthesis of PROTACs [1].

N-(Boc-PEG5)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-derived PROTAC linker used in PROTAC synthesis[1].

NH-bis(PEG4-acid) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

C2-Bis-phosphoramidic acid diethyl ester is an alkyl chain-derived PROTAC linker used in the synthesis of PROTACs [1].

Bis-PEG17-acid, a PEG-based linker for PROTACs, joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG5-acid (PROTAC Linker 36) is a polyethylene glycol (PEG) linker used in the synthesis of CP5V, a PROTAC that selectively degrades Cdc20[1].

N-Mal-N-bis(PEG2-acid) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system in cells.

N-Boc-N-bis(PEG3-acid) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

N-(PEG3-acid)-N-bis(PEG3-amine) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

N-Boc-N-bis(PEG4-acid) is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras] that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-PEG29-acid, a PEG-based linker for PROTACs, connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

3,5-Bis-O-(4-methylbenzoyl)-2-C-methyl-D-ribonic acid gama-lactone is a carbohydrate derivative.

N-(Azido-PEG3)-N-bis(PEG3-acid) is a polyethylene glycol (PEG)-based linker that incorporates an azido group and two PEG3-acid moieties, widely applicable in the synthesis of proteolysis targeting chimeras (PROTACs) for the selective degradation of target proteins[1].

Bis-PEG8-acid, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs and antibody-drug conjugates (ADCs)[1]. It serves as a cleavable ADC linker, facilitating the development of specialized compounds.

1-Aminodecylidenebis-phosphonic acid, with its potent inhibitory effect on acid sphingomyelinase (IC50= 20 nM), shows selectivity by being less effective against neutral sphingomyelinase (IC50= >100 μM). Additionally, it entirely prevents dexamethasone-induced apoptosis in HepG2 cells.