tenuifolia

Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxant activities, and attenuates Aβ1-42-induced oxidative stress and apoptosis by inducing autophagy.SB-674042 is used for the treatment of depression.SB-674042 is used for the treatment of depression.SB-674043 is used for the treatment of depression.SB-674044 is used for the treatment of depression.SB-674045 is used for the treatment of depression. 2A (BU-1) cell differentiation.

Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia.

Glomeratose A, a lactate dehydrogenase inhibitor (LDH), [Compound BBX] is a small molecule that targets enzyme inhibitors (MJBB-_13798), effectively reducing lactate production in cells, thereby influencing metabolic processes and demonstrating potential therapeutic applications in conditions characterized by elevated lactate levels.

Tenuifoliside C, isolated from Polygala tenuifolia Willd, is a targeted lactate dehydrogenase inhibitor that significantly inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1[1].

Polygalaxanthone XI is an xanthone glycoside isolated from the cortex of Polygala tenuifolia, which can be used in studies of expectorants and to promote psychostability.

Polygalaxanthone XI is an xanthone glycoside isolated from the cortex of Polygala tenuifolia, which can be used in studies of expectorants and to promote psychostability.

Tenuifoliose A is a natural product from Polygala tenuifolia Willd.

Onjisaponin Z is a natural product known as a triterpenoid saponin, characterized by its molecular structure that includes a sapogenin (aglycone) attached to one or more sugar moieties. Commonly found in the root of the medicinal herb Polygala tenuifolia, Onjisaponin Z exhibits a range of pharmacological effects, such as neuroprotective, anti-inflammatory, and antioxidant activities.

Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.

Desacylsenegasaponin B, an active compound extracted from the root of Polygala tenuifolia, exhibits potential anti-inflammatory activity [1].

Sibiricaxanthone A (Sibiricaxanthone A) is a natural product from Polygala tenuifolia

Arillanin A is a natural product from Polygala tenuifolia Willd.

7-O-MethylMangiferin is an xanthone isolated from the rhizomes of Iris nigricans.

Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk medicine.

Polygalic acid (Senegenic acid), a triterpenoid saponin, is a major active ingredient in Polygala tenuifolia. Polygalic acid shows expectorant, emetic and stimulant effects.

Onjixanthone II is a natural product from Polygala tenuifolia.

1,2,3,7-Tetramethoxyxanthone is a natural compound extracted from Polygala tenuifolia Willd.

Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.

Polygalacic acid (Virgaureagenin G) is a triterpenoid isolated from the root of Polygala tenuifolia Willd that inhibits MMP expression. Polygalacic acid (Virgaureagenin G) can significantly improve the responsiveness of the cholinergic system, such as decreased acetylcholinesterase (AChE) activity, increased choline acetyltransferase (ChAT) activity, and increased acetylcholine (ACh) levels in the hippocampus and frontal cortex. Polygalacic acid (Virgaureagenin G) can also inhibit IL-1β-induced Wnt β-catenin activation and mitogen-activated protein kinase (MAPK) signaling pathways in chondrocytes, and is used in osteoarthritis (OA) related research.

Tenuiphenone B, a benzophenone derivative, was isolated from the ethanolic extract of Polygala tenuifolia.

1,2,3,6,7-Pentamethoxyxanthone is a natural product from Polygala tenuifolia.

Tenuifoliose J is a natural product from Polygala tenuifolia Willd