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tubulin inhibitor-24

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    42
    TargetMol | Activity
Tubulin inhibitor 24
T98122415761-65-6In house
Tubulin inhibitor 24 is a potent compound that inhibits tubulin polymerization.
  • $117
In Stock
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QTY
TargetMol | Inhibitor Sale
Tubulin inhibitor 32
T787012923531-39-7In house
Tubulin inhibitor 32 is an orally active novel microtubule inhibitor with antiproliferative and antitumor activity, inhibits microtubule polymerization, induces apoptosis and cell cycle arrest in G2/M phase.
  • $293 TargetMol
In Stock
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Tubulin inhibitor 35
T775842247047-77-2
Tubulin inhibitor 35 (Tubulin IN 35) is a potent dual inhibitor of topoisomerase I and microtubule protein polymerization with antitumor activity, inhibits migration and invasion of MGC-803 and RKO cell lines, interrupts the cell cycle and induces apoptosis.
  • $54
In Stock
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Tubulin inhibitor 8
T132261309925-39-0In house
Tubulin inhibitor 8 is an inhibitor of tubulin and various cancer cell lines and inhibits tubulin polymerisation and K562 cell growth with an IC50 of 0.73 μM and 14 nM respectively.
  • $350
In Stock
Size
QTY
Eg5 Inhibitor V, trans-24
T11155869304-55-2In house
Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 μM, suitable for use in cancer research.
  • $93
In Stock
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QTY
TargetMol | Inhibitor Sale
Tubulin inhibitor 6
T13224105925-39-1
Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.
  • $43
In Stock
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QTY
TargetMol | Inhibitor Sale
BRD4 Inhibitor-24
T9629309951-18-6
BRD4 Inhibitor-24 is a BRD4 small molecule inhibitor with antitumor activity.
  • $38
In Stock
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TargetMol | Inhibitor Sale
Tubulin inhibitor 38
T78773
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell cycle at the G2/M phase, ultimately triggering apoptosis. Administered at 100 nM for 24 hours, it shows considerable cytotoxicity and selectivity within HeLa, MCF7, and U87 MG cell lines [1].
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Tubulin polymerization-IN-24
T60936564468-51-5
Tubulin polymerization-IN-24 (compound HMBA) is a potent inhibitor of tubulin polymerization, increasing GTP hydrolysis rate and inhibiting microtubule assembly. It induces apoptosis and cell cycle arrest in the G2 M phase, and inhibits the proliferation of MCF-7 cells [1].
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 41
T875732770273-12-4
Tubulin inhibitor 41 (Compd D19) is a promising lead compound for glioblastoma treatment, known for its ability to penetrate the blood-brain barrier (BBB). It functions as a tubulin inhibitor, inducing G2 M phase arrest, leading to cell apoptosis, and inhibiting the migration of U87 cells [1].
  • Inquiry Price
10-14 weeks
Size
QTY
Tubulin inhibitor 43
T875751541208-02-9
Tubulin inhibitor 43 exhibits significant antitumor activity by impeding the proliferation and growth of cancer cells through the inhibition of β-microtubulin activity, ultimately inducing apoptosis [1].
  • Inquiry Price
10-14 weeks
Size
QTY
Tubulin inhibitor 36
T78771
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells, reflected by an IC50 value of 1.5±0.1 μM. Exhibiting significant anti-mitotic activity, this compound demonstrates anti-tumor potential, particularly useful in glioblastoma multiforme (GBM) research [1].
  • Inquiry Price
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Tubulin inhibitor 37
T78772
Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell lines, showing promise for cancer research [1].
  • Inquiry Price
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Tubulin inhibitor 33
T789172944462-67-1
Tubulin Inhibitor 33 is a dose-dependent inhibitor of tubulin polymerization, exhibiting an IC50 value of 9.05 μM. This compound demonstrates antitumor activity and induces apoptosis, making it useful for antitumor research [1].
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 14
T60402
Tubulin inhibitor 14 is a potent inhibitor of NQO2 (quinone oxidoreductase 2) with an IC50 of 1.0 μM, which also inhibits tubulin polymerization and the formation of endothelial cell capillary-like tubes. As a microtubule destabilizer, Tubulin inhibitor 14 has potential tumor-selective, anti-angiogenic, and vascular-destructive properties [1].
  • $1,520
10-14 weeks
Size
QTY
Tubulin inhibitor 1
T132272237054-53-2
Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular mitotic arrest in the G2/M phase.
  • $46
5 days
Size
QTY
Tubulin inhibitor 28
T6154571112-91-9
Tubulin Inhibitor 28 (compound 2g), with an IC50 value of 1.2 μM, is a potent inhibitor of tubulin that exhibits significant anti-proliferative activity against MCF-7 cells [1].
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 21
T73832
Tubulin Inhibitor 21 (compound 6f), a hybrid based on chalcone and melatonin, exhibits potent tubulin inhibition properties. It demonstrates significant cytotoxic activity against SW480 cells (IC 50 =0.26 μM) while showing lesser effects on nonmalignant cells [1].
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Tubulin inhibitor 7
T132251309925-41-4
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC50: 11 nM)).
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 12
T6124292575-00-3
Tubulin inhibitor 12 (Hit 9) is a recently developed compound with potent tubulin inhibitory effects (IC50 = 25.3 μM) and significant anti-tumor and anti-proliferative activities, making it a promising candidate for cancer treatment [1].
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 26
T607932379241-70-8
Tubulin inhibitor 26 (compound 3c) is an indazole derivative and a potent tubulin inhibitor with low nanomolar potency against HepG2, HCT116, SW620, HT29, and A549 cancer cell lines. It inhibits tumor cells in the G2 M phase, induces cell apoptosis, and suppresses tumor growth in vivo without affecting mice body weight [1].
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 44
T875763025180-36-0
Tubulin Inhibitor 44 (Compound 26r) is an inhibitor of tubulin that exhibits cytotoxicity in cancer cells NCI-H460, BxPC-3, and HT-29, with IC50 values of 0.96, 0.66, and 0.61 nM, respectively [1].
  • Inquiry Price
10-14 weeks
Size
QTY
Tubulin inhibitor 42
T875742135713-96-9
Tubulin inhibitor 42 impedes the activity of β-microtubulin in a dose-dependent manner (IC 50 = 3.5 µM). It disrupts microtubule dynamic homeostasis, leading to G2 M phase arrest of the cancer cell cycle and inducing apoptosis. Additionally, Tubulin inhibitor 42 significantly hinders angiogenesis both in vitro and in vivo, thereby preventing vascularization and tumor growth [1].
  • Inquiry Price
10-14 weeks
Size
QTY
Tubulin inhibitor 34
T78761
Tubulin Inhibitor 34 (compound b5), a potent anticancer agent, inhibits tubulin polymerization and induces G2/M arrest and apoptosis. The compound demonstrates significant antivascular and antitumor activity [1].
  • Inquiry Price
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Tubulin inhibitor 16
T60460
Tubulin inhibitor 16 is a potent tubulin inhibitor that exhibits antiproliferative activity and cytotoxicity in HepG2 cells [1].
  • $1,520
10-14 weeks
Size
QTY
Tubulin inhibitor 31
T72449
Tubulin Inhibitor 31 is a potent compound with an inhibitory concentration (IC 50) of 4 µM, demonstrating significant anti-proliferative activity and the ability to inhibit HUVEC migration.
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 13
T623322883436-66-4
Tubulin Inhibitor 13 (E27) effectively inhibits tubulin polymerization with an IC50 of 16.1 μM. This compound also restricts cancer cell migration and invasion, promotes apoptosis, and exhibits notable anticancer activity [1].
  • $1,520
10-14 weeks
Size
QTY
Tubulin inhibitor 15
T60459
Tubulin inhibitor 15 is a potent tubulin inhibitor with antiproliferative activity, exhibiting cytotoxicity in HepG2 cells [1].
  • $1,520
10-14 weeks
Size
QTY
Tubulin inhibitor 25
T629222411697-71-5
Tubulin inhibitor 25 is a potent tubulin inhibitor (IC50: 0.98 μM) that significantly inhibits HT29 cells, impedes cell migration and microtubule formation, and contributes to anti-angiogenesis.
  • $1,520
8-10 weeks
Size
QTY
HIV-1 inhibitor-24
T624302475658-75-2
HIV-1 inhibitor-24 (compound S-12a) is a potent inhibitor of HIV-1 reverse transcription (HIV-1 RT) with an IC50 of 9.5 nM. It exhibits a high antiviral effect on wild-type HIV-1, showing an EC50 value of 1.6 nM and low cytotoxicity (CC50 on MT-4 cells). HIV-1 inhibitor-24 was well tolerated in mice at a dose of 2 g kg and demonstrated a significant cardiovascular safety profile.
  • $2,140
6-8 weeks
Size
QTY
Tubulin inhibitor 30
T724452873383-67-4
Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 18
T614722762382-51-2
Tubulin inhibitor 18 (compound 5j) is a highly potent chalcone compound that effectively inhibits tubulin, making it a promising candidate for cancer research [1].
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 22
T62445
Tubulin inhibitor 22 (compound 4c) is a potent tubulin inhibitor exhibiting anti-angiogenic and anti-cancer activity, which blocks the cell cycle of MGC-803 cells in the G2 M phase and induces Caspase-mediated apoptosis through mitochondrial dysfunction in a dose-dependent manner.
  • $1,520
10-14 weeks
Size
QTY
KRAS G12D inhibitor 24
T887203033701-29-7
KRAS G12D Inhibitor 24 (compound 103) is an effective inhibitor of KRAS G12D with an IC50 of 0.004 μM. It exhibits oral bioactivity.
  • Inquiry Price
10-14 weeks
Size
QTY
Tubulin inhibitor 23
T63120170488-57-0
Tubulin inhibitor 23 is a potent tubulin inhibitor (IC50: 4.8 μM) that exhibits antiangiogenic effects in a dose-dependent manner and induces apoptosis. This compound shows potential for leukemia research.
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 20
T60755860356-56-5
Tubulin inhibitor 20 (compound 1) exhibits significant potential for cancer research as a potent tubulin inhibitor [1].
  • $1,520
6-8 weeks
Size
QTY
Tubulin inhibitor 19
T61459
Tubulin inhibitor 19 (compound 9b) is a potent indole chalcone compound exhibiting strong tubulin inhibitory activity, making it valuable for cancer research [1].
  • $1,520
10-14 weeks
Size
QTY
Tubulin inhibitor 27
T61190184579-57-5
Tubulin Inhibitor 27 (DYT-1), a compound that inhibits tubulin polymerization with an IC50 of 25.6 μM, exhibits anti-angiogenesis and antitumor activities [1].
  • $1,520
6-8 weeks
Size
QTY
PKA Inhibitor (5-24) (trifluoroacetate salt)
T36019
PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki= 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein.1It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite.1The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr235and Phe239form a sandwich-like structure with residue Phe10of PKI (5-24).2
  • $183
35 days
Size
QTY
Tubulin inhibitor 29
T605682905-15-9
Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor that disrupts tubulin assembly by binding at the colchicine site (IC50 = 1.2 μM), and exhibits antiproliferative effects on MCF-7 cells with an IC50 value of 7.5 μM. [1].
  • $2,140
6-8 weeks
Size
QTY
Tubulin inhibitor 17
T60436
Tubulin inhibitor 17 (Compound 3b) is an inhibitor of tubulin polymerization (IC50 = 12.38 µM) that exhibits anticancer activities and induces cell apoptosis[1].
  • $1,520
10-14 weeks
Size
QTY
Tubulin inhibitor 11
T679352366260-33-3
Tubulin Inhibitor 11 is a potent, orally active agent that inhibits tubulin by targeting the Colchicine binding site. It impedes tubulin polymerization, leading to mitotic blockade and apoptosis.
  • $50
In Stock
Size
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