Sulfachloropyridazine (Sulfachlorpyridazine) is a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.Alfuzosin has been used to study benign prostatic hypertrophy, lower urinary tract symptoms (LUTS), and ejaculatory dysfunction (EjD).

Sulfalene (SMP2), a long-acting sulfonamide antibiotic, is used for the therapy of chronic bronchitis, urinary tract infections, and malaria.

Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic

Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.

Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.

Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action.

Sitafloxacin (Sitafloxacin anhydrous) is an orally active fluoroquinolone antibiotic with broad-spectrum antimicrobial activity.Sitafloxacin has been used in the study of respiratory tract infections and urinary tract infections.

Omadacycline (Amadacycline), a new tetracycline antibiotic, can inhibit the 30s subunit of bacterial ribosome.

3,4,5-Trimethoxybenzaldehyde shows anti-Candida efficacy and inhibits adhesion and biofilms.

Talampicillin is an ester of Ampicillin. It is hydrolyzed upon absorption to release ampicillin. It is well absorbed from the gastrointestinal tract resulting in a greater bioavailability of ampicillin than can be achieved with equivalent doses of ampicil

iKIX1 is an Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection.

Sulfacetamide sodium (Sulamyd sodium) is an anti-infective agent. It is used topically to treat orally for urinary tract infections and skin infections.

Nitrofural is the nitrofurans that have become established in clinical use in the 20th century. Nitrofural has remained clinically useful against a wide spectrum of gram-positive and gram-negative bacteria, including many strains of common urinary tract pathogens.

6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. Among the common bacteria causing urinary infection, only P. aeruginosa produces 6-hydroxynicotinic acid from nicotinic acid.

Cefonicid monosodium is the salt form of Cefonicid (free base), a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Fexapotide (NX-1207 free acid) selectively induces apoptosis, effectively reducing prostate volume at the cellular level. This compound is applicable in the research of lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) [1] [2] [3].

Pazufloxacin (T-3761) is a fluoroquinolone antibiotic targeting antibacterial applications. This compound, a novel quinolone derivative, has demonstrated robust and extensive antibacterial efficacy. Its effectiveness spans systemic, pulmonary, and urinary tract infections in mice, effectively combating both gram-positive and gram-negative bacteria, including strains resistant to quinolones such as Serratia marcescens and Pseudomonas aeruginosa. Compared to existing antibiotics like ofloxacin, ciprofloxacin, norfloxacin, and tosufloxacin, Pazufloxacin shows comparable or superior efficacy across various infection models. While slightly less effective than tosufloxacin against certain gram-positive infections, it remains potent against methicillin-resistant Staphylococcus aureus infections. Its broad-spectrum activity is further evidenced by minimum inhibitory concentrations (MICs) ranging from 0.39 to 6.25 micrograms/ml against various Staphylococcus aureus and Clostridium species, with minimum bactericidal concentrations (MBCs) typically equal to or within twofold of the MICs. Additionally, its 50% inhibitory concentrations for DNA gyrases from E. coli and P. aeruginosa stand at 0.88 and 1.9 micrograms/ml, respectively, underscoring its potent antibacterial mechanism of action.

Cefonicid (free base) is a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, heart rate changes, and bronchial spasm.

Phenazopyridine hydrochloride (Pyridium) is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include nausea, interference with the oxygen-carrying capacity of red blood cells (methemoglobinemia), hemolytic anemia as well as renal and hepatic toxicity. It is reasonably anticipated to be a human carcinogen.

Ceftolozane Sulfate may be used to treat urinary tract infections.

Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.

Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections.

Nitroxoline (5-nitroquinolin-8-ol) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.

Carbavance, a mixture of Meropenham and Vaborbactam, is intended for adults with complex urinary tract infections (cUTI), including pyelonephritis, a kidney infection caused by certain bacteria.

Sitafloxacin hydrochloride (DU6859a), a potent fluoroquinolone antibiotic with oral activity, demonstrates antichlamydial activity and a broad antibacterial spectrum against gram-positive, gram-negative, and anaerobic bacteria, in addition to atypical pathogens. It is utilized in researching respiratory tract and urinary tract infections [1] [2].

RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor

Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.

Piromidic acid is an antibacterial agent. Piromidic acid is active against gramnegative bacteria and staphylococci. It is used for urinary tract and intestinal infections.

Sitafloxacin Hydrate (DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.

Sulfadimethoxine is a antimicrobial agent, treatment of respiratory, urinary tract, enteric, and soft tissue infections

Mecillinam (Hexacillin), an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat urinary tract infections and has also been used in the treatment of paratyphoid fever and typhoid.

Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.

Phenazopyridine is commonly utilized as a local analgesic to mitigate pain, irritation, discomfort, or urgency resulting from urinary tract infections, surgical procedures, or injuries affecting the urinary tract [1].

Carindacillin sodium, also known as Carbenicillin indanyl sodium, is an orally active, broad-spectrum antimicrobial agent. In vivo, it undergoes hydrolysis to Carbenicillin. Carindacillin sodium is specifically utilized in urinary tract infection research.

Etzadroxil (Ethyl 2-Ethylbutyrate) is an orally available and volatile esterification.Etzadroxil has broad-spectrum antimicrobial activity for the treatment of urinary tract infections caused by multi-drug resistant bacteria.

Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.

Sulfadimethoxine (Sulphadimethoxine) is a sulfanilamide that is used as an anti-infective agent.

Sitafloxacin-d4 is a deuterated compound of Sitafloxacin. Sitafloxacin has a CAS number of 127254-12-0. Sitafloxacin (Sitafloxacin anhydrous) is an orally active fluoroquinolone antibiotic with broad-spectrum antimicrobial activity.Sitafloxacin has been used in the study of respiratory tract infections and urinary tract infections.

Sulfameter-d4 is a deuterated compound of Sulfameter. Sulfameter has a CAS number of 651-06-9. Sulfameter is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.

Levofloxacin-d8 is a deuterated compound of Levofloxacin. Levofloxacin has a CAS number of 100986-85-4. Levofloxacin is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.

Finafloxacin, a fluoroquinolone antimicrobial agent from a new 8-cyano subclass, is most effective in slightly acidic environments (pH 5.0-6.0), a condition where other fluoroquinolones typically reduce in activity. It selectively targets bacterial type II topoisomerases, such as DNA gyrase and DNA topoisomerase IV, making it suitable for treating serious bacterial infections particularly in acidic contexts, including urinary tract infections (UTIs) and Helicobacter pylori infections.

Dicyclonon is a muscarinic antagonist utilized as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It has some local anesthetic properties and is utilized in biliary, gastrointestinal,

Carfecillin Sodium is the phenyl ester of Carbenicillin, it is broken down in the intestinal mucosa to the active antibacterial upon oral administration. Carfecillin Sodiumis used for urinary tract infections.

Sulfametrole is an orally active and potent antibacterial that can be used in the research of infections, for example, HIV, severe pneumonia, and UTIs (urinary tract infections) [1] [2].

Motugivatrep is a potent type 1 transient receptor potential (TRPV1) antagonist and has a broad role in the treatment of drug, urinary tract and respiratory diseases.

Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.

Sulfachloropyridazine-d4 is a deuterated compound of Sulfachloropyridazine. Sulfachloropyridazine has a CAS number of 80-32-0. Sulfachloropyridazine is a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entire urinary tract following parenteral administration.