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By Target- Estrogen Receptor/ERR
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Results for "
y134
" in TargetMol Product Catalog- Inhibitors & Agonists1
Y134
T23540849662-80-2
Y134 is an estrogen receptor inhibitor that is selective and orally active, exhibiting strong antagonist activity against ERα and Erβ with Ki of 0.09 nM and 11.31 nM, respectively. The selectivity of Y134 for ERα is 121.1 times higher than that for ERβ. Y134 inhibited the proliferation of ER positive human breast cancer cells stimulated by estrogen.
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