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ysk 3

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MST1 Protein, Human, Recombinant (His)
TMPY-04398
Dysregulation of MST1 STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4 Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine threonine-protein kinase 4 (STK4) differentially regulates TLR3 4 9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a diagnostic biomarker and therapeutic target for inflammation-induced HCC.
  • $498
7-10 days
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