T14390 |
Azelaprag
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2049980-18-7
|
98%
|
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Azelaprag is an effective small-molecule apelin receptor agonist. Azelaprag can be used to treat neurological diseases and cardiovascular diseases.
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T14390L |
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide
|
2049979-31-7
|
98%
|
|
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist w...
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T35374L |
(Ala13)-Apelin-13 acetate
|
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98%
|
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(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier.
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TP1922L1 |
ELA-11 (human) acetate(1784687-32-6 free base)
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TP1922L1
|
98%
|
|
ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulate...
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T39823L |
Apelin-12 acetate
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T39823L
|
98%
|
|
Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-r...
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T10843 |
CMF019
|
1586787-08-7
|
98%
|
|
CMF019 is a potent agonist of the Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ (pKis: 8.58, 8.49, and 8.71 for the human, rat, and mouse).
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T4390 |
ML221
|
877636-42-5
|
98%
|
|
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the...
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TP1260 |
[Pyr1]-Apelin-13
|
217082-60-5
|
98%
|
|
[Pyr1]-Apelin-13 is a potent and selective endogenous Apelin receptor (APJ) agonist.
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TP1923L1 |
ELA-14(human) acetate
|
TP1923L1
|
98%
|
|
ELA-14(human) acetate is a fragment of ELA that binds to APJ, activates the Gαi1 and β-arrestin-2 signaling pathways, and induces receptor internalization simila...
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TP1364L |
ALX 40-4C acetate
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TP1364L
|
98%
|
|
ALX 40-4C acetate is a CXCR4 inhibitor of the chemokine receptor (Ki = 1 μM) and suppresses the replication of X4 strains of HIV-1. ALX 40-4C acetate is an antag...
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