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CRM1

Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is a eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA.
Cat No. product name
T15735 Leptomycin B Leptomycin B is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inact...
T1844 KPT330,(E)- KPT-330 is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothel...
T2425 KPT185 KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
T11837 Leptomycin A Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B. Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that bloc...
T6074 KPT276 KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
T6106 Selinexor (KPT-330) Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic a...
T14885 CBS9106 CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a ...
Leptomycin B
T15735
Leptomycin B is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inact...
KPT330,(E)-
T1844
KPT-330 is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothel...
KPT185
T2425
KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
Leptomycin A
T11837
Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B. Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that bloc...
KPT276
T6074
KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
Selinexor (KPT-330)
T6106
Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic a...
CBS9106
T14885
CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a ...