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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones Enzyme GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Compound Libraries Focused Bioactive Libraries Approved / Repurposing Characteristic Bioactive Libraries COVID-19 / SARS-CoV-2 Disease Focused Target / Pathway Focused Natural Product Libraries Characteristic Natural Product Libraries Natural Compound Library for HTS Fragment Libraries Diversity Sets Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones Enzyme GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling
Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Focused Bioactive Libraries Approved / Repurposing Characteristic Bioactive Libraries COVID-19 / SARS-CoV-2 Disease Focused Target / Pathway Focused
Natural Product Libraries Characteristic Natural Product Libraries Natural Compound Library for HTS Diversity Sets Golden Scaffold Library Mini Scaffold Library
Fragment Libraries Drug-fragment Library Featured Fragment Library High Solubility Fragment Library Custom Compound Library
Metabolism Carboxypeptidase(CPG2)

Carboxypeptidase(CPG2)

A carboxypeptidase is a protease enzyme that hydrolyzes (cleaves) a peptide bond at the carboxy-terminal (C-terminal) end of a protein or peptide. This is in contrast to an aminopeptidases, which cleave peptide bonds at the N-terminus of proteins. Humans, animals, bacteria and plants contain several types of carboxypeptidases that have diverse functions ranging from catabolism to protein maturation.
Cat No. product name
T3440 2-PMPA 2-PMPA is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).
T4345 CeMMEC1 CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
T6801 CeMMEC13 CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
2-PMPA
T3440CAS 173039-10-6
2-PMPA is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).
CeMMEC1
T4345CAS 440662-09-9
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
CeMMEC13
T6801CAS 1790895-25-8
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
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