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DNA gyrase

DNA gyrase is an essential bacterial enzyme that catalyzes the ATP-dependent negative super-coiling of double-stranded closed-circular DNA. Gyrase belongs to a class of enzymes known as topoisomerases that are involved in the control of topological transitions of DNA.
Cat No. product name
T0974 Novobiocin Sodium Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveu...
T13231 Trovafloxacin Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive.
T0717 Enoxacin hydrate Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
T1451 Levofloxacin hydrate Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxaci...
T1306 Norfloxacin Norfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
T1095 Sparfloxacin Sparfloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.
T2353 BRD7116 BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.
T0250 Ciprofloxacin monohydrochloride Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline.
T1294 Fleroxacin Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
T1492 Gemifloxacin mesylate Gemifloxacin mesylate inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Me...
TQ0063 Zoliflodacin Zoliflodacin (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-posit...
T0116 Balofloxacin Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.
T7786 Tryptanthrin Tryptanthrin is a natural DNA gyrase inhibitor.
T8747 Levofloxacin hydrochloride Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxac...
Novobiocin Sodium
T0974
Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveu...
Trovafloxacin
T13231
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive.
Enoxacin hydrate
T0717
Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
Levofloxacin hydrate
T1451
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxaci...
Norfloxacin
T1306
Norfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
Sparfloxacin
T1095
Sparfloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.
BRD7116
T2353
BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.
Ciprofloxacin monohydrochloride
T0250
Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline.
Fleroxacin
T1294
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
Gemifloxacin mesylate
T1492
Gemifloxacin mesylate inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Me...
Zoliflodacin
TQ0063
Zoliflodacin (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-posit...
Balofloxacin
T0116
Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.
Tryptanthrin
T7786
Tryptanthrin is a natural DNA gyrase inhibitor.
Levofloxacin hydrochloride
T8747
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxac...