DNA gyrase

DNA gyrase is an essential bacterial enzyme that catalyzes the ATP-dependent negative super-coiling of double-stranded closed-circular DNA. Gyrase belongs to a class of enzymes known as topoisomerases that are involved in the control of topological transitions of DNA.

Cat. No.	Product name	CAS No.	Purity
T8747	Levofloxacin hydrochloride	177325-13-2
T8747	Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxac...
T0250	Ciprofloxacin monohydrochloride	93107-08-5	97.10%
T0250	Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline.
T1451	Levofloxacin hydrate	138199-71-0	98.56%
T1451	Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxaci...
T13231	Trovafloxacin	147059-72-1	99.27%
T13231	Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive.
T0974	Novobiocin Sodium	1476-53-5	99.28%
T0974	Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveu...
T1294	Fleroxacin	79660-72-3	99.34%
T1294	Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
T1492	Gemifloxacin mesylate	210353-53-0	99.55%
T1492	Gemifloxacin mesylate inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Me...
TQ0063	Zoliflodacin	1620458-09-4	99.82%
TQ0063	Zoliflodacin (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-posit...
T0717	Enoxacin hydrate	84294-96-2	99.86%
T0717	Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
T2353	BRD7116	329059-55-4	99.91%
T2353	BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.
T7786	Tryptanthrin	13220-57-0	99.94%
T7786	Tryptanthrin is a natural DNA gyrase inhibitor.
T1095	Sparfloxacin	110871-86-8	99.95%
T1095	Sparfloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.
T1306	Norfloxacin	70458-96-7	99.97%
T1306	Norfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
T0116	Balofloxacin	127294-70-6	99.98%
T0116	Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.