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Cytoskeletal Signaling Dynamin

Dynamin

Dynamin is a GTPase responsible for exocytosis in the eukaryotic cell. Dynamin is part of the "dynamin superfamily", which includes classical dynamins, dynamin-like proteins, Mx proteins, OPA, mitofusins, and GBPs. Members of the dynamin family are principally involved in the scission of newly formed vesicles from the membrane of one cellular compartment and their targeting to, and fusion with, another compartment, both at the cell surface (particularly caveolae internalization) as well as at the Golgi apparatus. Dynamin family members also play a role in many processes including division of organelles, cytokinesis and microbial pathogen resistance.
Cat No. product name
T1848 Dynasore Dynasore, a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-free assay). It also in...
T1907 Mdivi 1 Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) (IC50: 1-10 ...
T6822 Dyngo-4a Dyngo-4a, an effective dynamin inhibitor, inhibits DynI (brain), DynI (rec), and DynII (rec) with IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respe...
Dynasore
T1848CAS 304448-55-3
Dynasore, a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-free assay). It also in...
Mdivi 1
T1907CAS 338967-87-6
Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) (IC50: 1-10 ...
Dyngo-4a
T6822CAS 1256493-34-1
Dyngo-4a, an effective dynamin inhibitor, inhibits DynI (brain), DynI (rec), and DynII (rec) with IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respe...