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GNRH Receptor

The gonadotropin-releasing hormone receptor (GnRHR), also known as the luteinizing hormone releasing hormone receptor (LHRHR), is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is the receptor of gonadotropin-releasing hormone (GnRH). The GnRHR is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T80116 LHRH 35263-73-1 98%
LHRH
Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has applicat...
T80422 Phoenixin-14 1415039-79-0 98%
Phoenixin-14
Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/reperfu...
T10988 Degarelix 214766-78-6 98%
Degarelix
Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.
T72492 GnRH-R antagonist 1 2826273-90-7 98%
GnRH-R antagonist 1
GnRH-R antagonist 1 (Compound 21a), is an orally active, membrane-permeable agent with a high binding affinity (IC50=0.57 nM) and potent in vitro antagonistic ef...
T21309 Nafarelin acetate(76932-56-4 free base) 76932-60-0 99.98%
Nafarelin acetate(76932-56-4 free base)
Nafarelin acetate(76932-56-4 free base) (RS-94991-298) is a GnRH agonist that acts as an analog of GnRH. Nafarelin acetate(76932-56-4 free base) causes a decreas...
T5031 Elagolix sodium 832720-36-2 99.93%
Elagolix sodium
Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).
TP2107L Histrelin acetate 220810-26-4 99.91%
Histrelin acetate
Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It acts on particular cells of the pituitary gland called ...
T21410 Triptorelin acetate(57773-63-4 free base) 140194-24-7 99.90%
Triptorelin acetate(57773-63-4 free base)
Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and ...
TP2323L Deslorelin acetate(57773-65-6 free base) TP2323L 99.84%
Deslorelin acetate(57773-65-6 free base)
Deslorelin acetate(57773-65-6 free base) is a gonadotropin releasing hormone super-agonist (GnRH agonist)
T27837 Linzagolix 935283-04-8 99.68%
Linzagolix
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharm...
T3630 Relugolix 737789-87-6 99.67%
Relugolix
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with po...
TP1700L LGnRH-III, lamprey acetate(147859-97-0 free base) TP1700L 99.66%
LGnRH-III, lamprey acetate(147859-97-0 free base)
LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretion of...
TP1307 Buserelin Acetate (57982-77-1 free base) 68630-75-1 99.23%
Buserelin Acetate (57982-77-1 free base)
Buserelin Acetate (57982-77-1 free base) (Buserelin Acetate) is an agonist of gonadotropin-releasing hormone receptor(GnRHR).
T22025 AG 045572 263847-55-8 98.99%
AG 045572
AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 is ...
T10988L Degarelix acetate(214766-78-6 free base) T10988L 98.66%
Degarelix acetate(214766-78-6 free base)
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
T5520L Cetrorelix diacetate 130143-01-0 98.38%
Cetrorelix diacetate
Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppres...
TP1434L Lecirelin acetate(61012-19-9 free base) TP1434L 98.1%
Lecirelin acetate(61012-19-9 free base)
Lecirelin acetate is a synthetic GnRH (gonadotropin releasing hormone) analogue which shows a great efficacy in the treatment of bovine ovarian follicular cysts....
T5520 Cetrorelix Acetate 145672-81-7 97.96%
Cetrorelix Acetate
Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.
T11174 (R)-Elagolix 834153-87-6 97.63%
(R)-Elagolix
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike in...
TP2337 Ganirelix Acetate 123246-29-7 96.05%
Ganirelix Acetate
Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist
LHRH
T80116
Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has applicat...
Phoenixin-14
T80422
Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/reperfu...
Degarelix
T10988
Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.
GnRH-R antagonist 1
T72492
GnRH-R antagonist 1 (Compound 21a), is an orally active, membrane-permeable agent with a high binding affinity (IC50=0.57 nM) and potent in vitro antagonistic ef...
Nafarelin acetate(76932-56-4 free base)
T21309
Nafarelin acetate(76932-56-4 free base) (RS-94991-298) is a GnRH agonist that acts as an analog of GnRH. Nafarelin acetate(76932-56-4 free base) causes a decreas...
Elagolix sodium
T5031
Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).
Histrelin acetate
TP2107L
Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It acts on particular cells of the pituitary gland called ...
Triptorelin acetate(57773-63-4 free base)
T21410
Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and ...
Deslorelin acetate(57773-65-6 free base)
TP2323L
Deslorelin acetate(57773-65-6 free base) is a gonadotropin releasing hormone super-agonist (GnRH agonist)
Linzagolix
T27837
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharm...
Relugolix
T3630
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with po...
LGnRH-III, lamprey acetate(147859-97-0 free base)
TP1700L
LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretion of...
Buserelin Acetate (57982-77-1 free base)
TP1307
Buserelin Acetate (57982-77-1 free base) (Buserelin Acetate) is an agonist of gonadotropin-releasing hormone receptor(GnRHR).
AG 045572
T22025
AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 is ...
Degarelix acetate(214766-78-6 free base)
T10988L
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
Cetrorelix diacetate
T5520L
Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppres...
Lecirelin acetate(61012-19-9 free base)
TP1434L
Lecirelin acetate is a synthetic GnRH (gonadotropin releasing hormone) analogue which shows a great efficacy in the treatment of bovine ovarian follicular cysts....
Cetrorelix Acetate
T5520
Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.
(R)-Elagolix
T11174
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike in...
Ganirelix Acetate
TP2337
Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist
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TargetMol