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Membrane transporter/Ion channel OAT

OAT

Organic anion transporters (OATs) are the secondary/tertiary active transporter proteins that regulate anion balance in the body. They are primarily expressed in the kidney and liver and control the excretion of common drugs, toxins, and endogenous metabolites into the urine.
Cat No. product name
T3994 Verinurad Verinurad (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.
T6875 Lesinurad Lesinurad is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited ...
T13259 URAT1 inhibitor 1 URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1)(IC50 of 32 nM), has potential to treat hyperuricemia associated with gout.
Verinurad
T3994CAS 1352792-74-5
Verinurad (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.
Lesinurad
T6875CAS 878672-00-5
Lesinurad is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited ...
URAT1 inhibitor 1
T13259CAS 2268720-62-1
URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1)(IC50 of 32 nM), has potential to treat hyperuricemia associated with gout.