Cart
Tyrosine Kinase/Adaptors PYK2

PYK2

Pyk2 is a Novel Tau Tyrosine Kinase that is Regulated by the Tyrosine Kinase Fyn,the protein tyrosine kinase Pyk2 is encoded by PTK2B,Pyk2 Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response,.
Cat No. product name
T1918 TAE226 NVP-TAE226 is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, an...
T2314 PF 431396 PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
T2465 PF-562271 PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
T6177 PF-562271 besylate PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selecti...
TAE226
T1918CAS 761437-28-9
NVP-TAE226 is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, an...
PF 431396
T2314CAS 717906-29-1
PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
PF-562271
T2465CAS 717907-75-0
PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
PF-562271 besylate
T6177CAS 939791-38-5
PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selecti...