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Croton

  • Kaurenoic acid
    T39296730-83-2
    Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part, by the opening of ATP-sensitive potassium channels. Kaurenoic acid exhibits an analgesic effect in a consistent manner and that its mechanisms involve the inhibition of cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. Kaurenoic acid derivatives have an antimicrobial activity of substituted on carbon-15 at concentrations greater than or equal to 250 μg ml. Kaurenoic acid has inhibitory effects on the LPS-induced inflammatory response in RAW264.7 macrophages.
    • $59
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  • Ferulamide
    TN164361012-31-5
    Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.
    • $185
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  • 3-O-Methylquercetin
    TN12661486-70-0
    3-O-Methylquercetin is a selective and competitive PDE3 PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low K(m) value; it inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.
    • $89
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  • Crotonoside
    T6S00331818-71-9
    1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig and hamster and in stimulating the isolated uterus of guinea pigs and hamsters. 2. Crotonoside inhibits the growth of S-18 and Ehrlich solid tumor in mice at the optimal doses of 96 mg kg day x 12 and 48 mg kg day x 12, with 1-T C values of 65% and 6%, respectively.
    • $30
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  • ent-3-Oxokauran-17-oic acid
    TN3945151561-88-5
    ent-3-Oxokauran-17-oic acid is a natural product for research related to life sciences. The catalog number is TN3945 and the CAS number is 151561-88-5.
    • $550
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  • Koaburaside
    TN439241653-73-0
    Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histamine release from mast cells.
    • $185
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  • Koaburaside monomethyl ether
    TN439341514-64-1
    Koaburaside monomethyl ether is a natural product of Croton, Euphorbiaceae. The catalog number is TN4393 and the CAS number is 41514-64-1. Koaburaside monomethyl ether can be used as a reference standard.
    • $127
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  • ent-kaurane-3,16,17-triol
    TN3959130855-22-0
    Kaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan- 3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia.
    • $740
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  • 3-O-Methylquercetin tetraacetate
    TN29741486-69-7
    Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiveness.
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  • ent-3-Oxokaurane-16,17-diol
    TN3946135683-73-7
    AKaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan-3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia.
    • $590
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  • Kongensin A
    T5136885315-96-8
    Kongensin A is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications.
    • $1,230
    6-8 weeks
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  • ent-17-Hydroxykauran-3-one
    TN3943960589-81-5
    ent-17-Hydroxy-16α-kauran-3-one shows weak antimicrobial activity when tested against Staphylococcusaureus.
    • $660
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