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Euphorbia

  • Phorbol 12-myristate 13-acetate
    TQ019816561-29-8
    Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB. Phorbol 12-myristate 13-acetate induces THP1 cell differentiation.
    • $50
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  • 20-O-Acetylingenol-3-angelate
    TQ009982425-35-2
    20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) is a natural compound found in the leaves and stems of the plant Inga. It has a variety of biological activities including tumor growth inhibition, anti-inflammatory, antifungal and antioxidant effects.
    • $219
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  • Lathyrol
    T3S201934420-19-4
    1.Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance.
    • $45
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  • Dodecanoic acid ingenol ester
    TQ016454706-70-6
    Dodecanoic acid ingenol ester, a natural compound, shows moderate cytotoxicity with IC50 values being 35.59 μM (Caco-2), 24.04 μM (MCF-7), and 22.24 μM (MCF-7/ADM).
    • $498
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  • Fischeria A
    TN4059221456-63-9
    Fischeria A is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN4059 and the CAS number is 221456-63-9. Fischeria A can be used as a reference standard.
    • $750
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  • Gopherenediol
    TN5597916236-79-8
    Gopherenediol shows weak antifeedant activity.
    • $820
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  • Pepluanin A
    TN4749670257-89-3
    Pepluanin A, shows a very high activity for a jatrophane diterpene, outperforming cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated daunomycin transport.
    • $2,210
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  • Ebracteolata cpd B
    TN390983459-37-4
    Ebracteolata cpd B is a natural product for research related to life sciences. The catalog number is TN3909 and the CAS number is 83459-37-4.
    • $498
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  • Euphorbia factor L7b
    TN163493550-95-9
    Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr.
    • $80
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  • Boehmenan
    TN352557296-22-7
    (±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell
    • $276
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  • ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide
    TN3932130466-20-5
    ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide shows significant cytotoxic activity against ANA-1 and Jurkat cells with IC50 values 7.12 x 10(-3) and 1.79 x 10(-2) microM.
    • $268
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  • Euphorbia Factor L2
    T5798218916-51-9
    Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.
    • $80
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  • Ingenol-3,4,5,20-diacetonide
    TN176577573-44-5
    Tropine is a secondary metabolite of the Solanaceae family of plants and is an anticholinergic reagent. It is a common intermediate used in the synthesis of various biologically active alkaloids (e.g. hyoscyamine, scopolamine).
    • $133
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  • ent-Kaurane-16beta,19,20-triol
    TN3958167898-32-0
    ent-Kaurane-16beta,19,20-triol is a natural product for research related to life sciences. The catalog number is TN3958 and the CAS number is 167898-32-0.
    • $660
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  • ent-Atisane-3beta,16alpha,17-triol
    TN3957115783-44-3
    ent-Atisane-3beta,16alpha,17-triol is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN3957 and the CAS number is 115783-44-3. ent-Atisane-3beta,16alpha,17-triol can be used as a reference standard.
    • $670
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  • Ingenol 3-palmitate
    TN425352557-26-3
    Ingenol-3-palmitate shows irritant and cocarcinogenic activity on mouse ear and on mice back skin.
    • $2,028
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  • Ingenol-5,20-acetonide
    TN104977573-43-4
    Maltol is a type of aromatic compound found in high concentrations in red ginseng and is a potent antioxidant used to enhance flavor and preserve food.
    • $138
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  • Epoxylathyrol
    T3S201628649-60-7
    Epoxylathyrol derivatives have modulation of ABCB1-mediated multidrug resistance in human colon adenocarcinoma and mouse T-Lymphoma cells.
    • $270
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  • 12-Ursene-3,16,22-triol
    TN26031242085-06-8
    12-Ursene-3,16,22-triol is a natural product for research related to life sciences. The catalog number is TN2603 and the CAS number is 1242085-06-8.
    • $293
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  • Orientalide
    TN656272704-05-3
    Orientalide is a natural product for research related to life sciences. The catalog number is TN6562 and the CAS number is 72704-05-3.
    • $630
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  • 20-Deoxyingenol 3-angelate
    TN279975567-38-3
    20-Deoxyingenol 3-angelate and ingenol 20-acetate 3-angelate are known as promoters of tumors of mouse skin. 20-Deoxyingenol 3-angelate can induce significant platelet aggregation accompanied by induction of phosphorylation of PKC substrates in platelets,
    • $670
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  • 2',4'-Dihydroxy-3'-methoxyacetophenone
    TN271762615-26-3
    2',4'-Dihydroxy-3'-methoxyacetophenone is a natural product for research related to life sciences. The catalog number is TN2717 and the CAS number is 62615-26-3.
    • $200
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  • Epitaraxerol
    TN397820460-33-7
    Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis.
    • $460
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  • Euphohelioscopin A
    TN559387064-61-7
    Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity
    • $660
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  • 3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one
    TN2890244277-75-6
    3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN2890 and the CAS number is 244277-75-6. 3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one can be used as a reference standard.
    • $660
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  • 5-hydroxythalidomide
    TN3098219916-77-5
    5-hydroxythalidomide is a natural product for research related to life sciences. The catalog number is TN3098 and the CAS number is 219916-77-5.
    • $660
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  • Simiarenone
    TN50252318-78-7
    Simiarenone is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN5025 and the CAS number is 2318-78-7. Simiarenone can be used as a reference standard.
    • $550
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  • ent-11β-Hydroxyatis-16-ene-3,14-dione
    TN39331092103-22-4
    ent-11β-Hydroxyatis-16-ene-3,14-dione is a natural product for research related to life sciences. The catalog number is TN3933 and the CAS number is 1092103-22-4.
    • $660
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  • (E)-Ferulic acid
    T5679537-98-4
    (E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.t(E)-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
    • $41
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  • Phorbol 13-acetate
    TN476832752-29-7
    Phorbol 13-acetate is a natural product for research related to life sciences. The catalog number is TN4768 and the CAS number is 32752-29-7.
    • $590
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  • 5,15-Diacetyl-3-benzoyllathyrol
    T4S2014218916-52-0
    1. 5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability.
    • $66
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  • Ingenol-5,20-acetonide-3-O-angelate
    TQ031687980-68-5
    Ingenol-5,20-acetonide-3-O-angelate (Ingenol 5,20-acetonide 3-angelate) is a natural product.
    • $79
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  • 17-Hydroxyisolathyrol
    TN119693551-00-9
    γ-L-Glutamyl-L-alanine consists of γ-glutamate and alanine, and is a substrate for CRF21 (γ-glutamyl cyclotransferase, GGCT), a proteolytic breakdown product of larger proteins.γ-L-Glutamyl-L-alanine is a positive regulator of calcium-sensitive receptor (CaR) function.
    • $42
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  • Jatrophane VI
    TN4354210108-90-0
    Jatrophane VI is a natural product for research related to life sciences. The catalog number is TN4354 and the CAS number is 210108-90-0.
    • $660
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  • 7beta-Hydroxylathyrol
    T2S201834208-98-5
    7β-Hydroxylathyrol is a diterpenoid extract from the seed oil of Caper Spurge and displays P-gp inhibition resulting in cytotoxic properties.
    • $66
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  • 5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane
    TN3097210108-91-1
    5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane is a natural product for research related to life sciences. The catalog number is TN3097 and the CAS number is 210108-91-1.
    • $660
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  • Ingenol mebutate
    TN104775567-37-2
    Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.
    • $64
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  • Jolkinol A
    TN435562820-11-5
    Jolkinol A can inhibit both MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) cell lines, with GI50 values ranging between 40.9 microM and 95.3 microM.
    • $720
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  • 9-O-Ethyldeacetylorientalide
    TN33241258517-60-0
    9-O-Ethyldeacetylorientalide is a natural product for research related to life sciences. The catalog number is TN3324 and the CAS number is 1258517-60-0.
    • $790
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  • Tirucallol
    TN1006514-46-5
    Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action related to the neutrophil migration.
    • $115
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  • Germanicol acetate
    TN413110483-91-7
    Germanicol acetate shows some slight cytotoxic activity against Jurkat cells .
    • $540
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  • Ingenol 20-palmitate
    TN425239071-33-5
    Ingenol 20-palmitate is a natural product from Euphorbia sieboldiana.
    • $550
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  • Euphorbia factor L1
    T2S041076376-43-7
    Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, anti-osteoclastogenic, and multidrug-resistant regulatory effects.
    • $100
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  • 31-Norlanostenol
    T1350316910-39-7
    31-Norlanostenol is a triterpene isolated from the latex of Euphorbia officinarum. It can act as an efficient insect growth regulator on S. frugiperda and Tenebrio molitor.
    • $1,520
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  • 1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose
    TN239025018-67-1
    1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose is a natural from Euphorbia macroclada
    • $480
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  • Cycloart-25-ene-3,24-diol
    TN373610388-48-4
    (24R)-Cycloart-25-ene-3beta,24-diol may be an anti-tumor promoter, it exhibits inhibitory effects on both Epstein-Barr virus early antigen (EBV-EA) and (+/-)-(E)-methtyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3- hexemide (NOR 1) activation.
    • $540
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  • Antiquorin
    TN3424125356-08-3
    Antiquorin exhibits moderate cytotoxic activities against the human lung cancer 95-D cell line with the IC50 value of 34.5 uM.
    • $620
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  • ent-16alpha,17-Dihydroxyatisan-3-one
    TN3937112523-91-8
    ent-16alpha,17-Dihydroxyatisan-3-one and ent-16alpha,17-dihydroxykauran-3-one have apoptosis induction activities on L5178 human MDR1 gene-transfected mouse lymphoma cells.
    • $520
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  • 4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one
    TN3032133369-42-3
    4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one is a natural product for research related to life sciences. The catalog number is TN3032 and the CAS number is 133369-42-3.
    • $590
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  • euphol
    T5737514-47-6
    Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action.
    • $84
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