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By Target- Apoptosis
- HDAC(1)
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Results for "
aes-350
" in TargetMol Product Catalog- Inhibitors & Agonists1
AES-350
T9041847249-57-4
AES-350 is a potent and orally active HDAC6 inhibitor (IC50 and Ki of 0.0244 μM and 0.035 μM, respectively), also exhibiting activity against HDAC-3, -8, and -11 in an enzymatic assay with IC50 values of 0.187 μM, 0.245 μM, and >1 μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
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